Dementia Clinical Trial
Official title:
Detecting Dementia in the Retina: a Big Data Machine Learning Approach
Verified date | September 2021 |
Source | Moorfields Eye Hospital NHS Foundation Trust |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This retrospective case control explores the retinal features of dementia associated with neurodegenerative diseases, particularly Alzheimer's disease. By linking a pseudonymised dataset of three-dimensional retinal scans, called optical coherence tomography, with nationally held data on dementia, corresponding characteristics will be evaluated through descriptive statistics and machine learning techniques.
Status | Active, not recruiting |
Enrollment | 280000 |
Est. completion date | August 1, 2022 |
Est. primary completion date | August 1, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 40 Years and older |
Eligibility | Inclusion Criteria: All patients over the age of 40 who have undergone an optical coherence tomography scan at Moorfields Eye Hospital NHS Foundation Trust Exclusion Criteria: Poor quality image |
Country | Name | City | State |
---|---|---|---|
United Kingdom | Moorfields Eye Hospital NHS Foundation Trust | London |
Lead Sponsor | Collaborator |
---|---|
Moorfields Eye Hospital NHS Foundation Trust |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Retinal nerve fiber layer thickness | 1 year | ||
Primary | Ganglion cell layer thickness | 1 year | ||
Primary | Macular volume | 1 year |
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