Dementia Clinical Trial
Official title:
Optimizing Prescribing of Antipsychotics in Long-Term Care (OPAL): A Randomized Trial to Reduce Inappropriate Antipsychotic Prescribing in Long-Term Care
Inappropriate antipsychotic prescribing is a key quality indicator by which clinical outcomes might be monitored and improved in LTC. A multi component intervention to reduce inappropriate antipsychotic prescribing was evaluated in ten Canadian long-term care facilities.
Increasing numbers of older adults are affected by dementia, and many will eventually reside
in long-term care (LTC), where antipsychotic use is relatively common. Inappropriate
antipsychotic prescribing is a key quality indicator by which clinical outcomes might be
monitored and improved in LTC but limited evidence exists on the most effective strategies
for reducing inappropriate antipsychotic use.
The objective of the study was to evaluate a multicomponent approach to reduce inappropriate
prescribing of antipsychotics in LTC.
A prospective, randomized stepped-wedge, study design was used to evaluate the effect of the
intervention in 10 LTC facilities in Canada. The intervention consisted of an educational
in-service, provision of evidence-based tools to assess and monitor neuropsychiatric symptoms
(NPS) and monthly interprofessional team meetings.
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