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Escitalopram for Agitation in Alzheimer's Disease — S-CitAD  

Dementia Clinical Trial

Official title:
Escitalopram for Agitation in Alzheimer's Disease

Clinical Trial Summary

The purpose of this study is to evaluate the safety and efficacy of escitalopram for agitation in Alzheimer's dementia.

Clinical Trial Description

This study is designed to examine the efficacy and safety of escitalopram as treatment for agitation in Alzheimer's dementia (AD) patients. Participants with clinically significant agitation, and their caregiver(s), will receive a structured psychosocial intervention. Participants not showing a response three weeks later will be randomized 1:1 to escitalopram (up to 15 mg/day) or a matching placebo. Participants will receive study drug or placebo for 12 weeks, with in-person and remote (phone/video) visits at weeks 3, 6, 9, and 12, and with telephone contacts between in-person and remote visits. Participants who do show a response to the psychosocial intervention will not be randomized to study drug but will be followed remotely. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03108846
Study type Interventional
Source JHSPH Center for Clinical Trials
Contact
Status Active, not recruiting
Phase Phase 3
Start date January 3, 2018
Completion date May 2025
View Details
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