Resource Use and Disease Course in Dementia (REDIC)

Dementia Clinical Trial

— REDIC  

Official title:

Resource Use and Disease Course in Dementia (REDIC)

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01920100
• Other study ID #: E13237
• Status: Completed
• Start date: April 2009
• Est. completion date: November 2023

Study information

• Verified date: November 2023
• Source: Sykehuset Innlandet HF
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This project is based on a three-year program that aims to improve the knowledge of the socioeconomic consequences of dementia in Norway. By including patients with and without dementia in four different cohorts (from nursing homes, from memory clinics, home-dwelling persons with dementia and elderly persons without dementia), the project's aim is to describe the course of dementia, the economical cost of dementia and to look into possible risk factors for dementia.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 696
• Est. completion date: November 2023
• Est. primary completion date: January 2015
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A and older

Eligibility

Memory clinic sample

Inclusion Criteria:

• All patients examined at a memory clinic with mild cognitive impairment or mild dementia

Exclusion Criteria:

• None

In-home care sample

Inclusion Criteria:

• Persons 70 years of age or older receiving in-home care from the municipality

Exclusion Criteria:

• None

Nursing-home sample

Inclusion Criteria:

• All persons admitted to the nursing home with an expected stay of more than four weeks.

• Participants should be 65 years or older, unless established dementia disease, in which case younger persons also will be included

Exclusion Criteria:

• Life expectancy of less than six weeks

Control sample

Inclusion Criteria:

• Persons 65 years or older without any sign of dementia

Exclusion Criteria:

• None

Related Conditions & MeSH terms

• Dementia
• Disease Progression
• Neurodegenerative Diseases

Locations

Country	Name	City	State
Norway	University of Bergen	Bergen
Norway	Senter for omsorgsforskning - Midt	Namsos
Norway	Innlandet Hospital Trust	Ottestad

Sponsors (10)

Lead Sponsor	Collaborator
Sykehuset Innlandet HF	Helse Midt-Norge, Karolinska Institutet, King's College London, Norwegian Centre for Ageing and Health, Norwegian Directorate of Health, Norwegian University of Science and Technology, Oslo University Hospital, University Hospital, Akershus, University of Bergen

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cost of dementia	The cost of dementia is assessed with the Resource Utilization in Dementia (RUD) (Wimo et al. 2009), for a period of three years for all the four cohorts. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.	3 years
Secondary	The course of neuropsychiatric symptoms	The course of neuropsychiatric symptoms (depression, anxiety, psychosis, aggression, apathy, and cognition, are assessed with standardized assessment Tools. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.	3 years
Secondary	Quality of Life in persons admitted to nursing homes	Quality of Life is assessed with standardized assessment Tools. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.	3 years
Secondary	Prescription of medication	Prescription of medication is recorded at baseline, and the amount of medication used is recorded throughout the study period. The nursing home cohort is assessed at baseline and every 6 month for three years, the other three cohorts are assessed three times over a three-year follow up period.	3 years
Secondary	DNA polymorphism	DNA samples are collected for the nursing home cohort, and they are assessed for genetic polymorphism previous associated with dementia. The results are used as covariates in the analyses of the course of the symptoms and to look for risk factors for dementia.	At baseline
Secondary	Organizational factors of the nursing homes	Organizational factors of the nursing homes and variables associated with the staff of the nursing homes will be collected at baseline, and the data will be used to explore associations between nursing home characteristics and the course of the symptoms in the patients.	At baseline

External Links

•   Link to web page with a working paper describing the project