Mirtazapine in Alzheimer-associated Weight Loss

Dementia Clinical Trial

Official title:

Mirtazapine in Alzheimer-associated Weight Loss: a Retrospective Phase IV Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01505504
• Other study ID #: MIRTA-2012
• Status: Completed
• Phase: N/A
• First received: January 4, 2012
• Last updated: January 5, 2012
• Start date: January 2004
• Est. completion date: December 2011

Study information

• Verified date: January 2012
• Source: Brugmann University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Belgium: Federal Agency for Medicinal Products and Health Products
• Study type: Observational

Clinical Trial Summary

Weight loss is a frequent problem associated with Alzheimers disease (AD). Mirtazapine has weight loss as a frequent side effect.

The aim of this retrospective study is to check whether mirtazapine 30 mg (once daily) can counteract weight loss in patients with AD or mixed dementia (AD + vascular).

Recruitment information / eligibility

• Status: Completed
• Enrollment: 22
• Est. completion date: December 2011
• Est. primary completion date: November 2011
• Accepts healthy volunteers: No
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• AD or mixed dementia

• documented weight loss

• mirtazapine 30 mg explicitly prescribed against weight loss

Exclusion Criteria:

• no treatment compliance

• other causes of weight loss

• other interventions against weight loss

Study Design

Observational Model: Case-Only, Time Perspective: Retrospective

Related Conditions & MeSH terms

• Alzheimer Disease
• Alzheimer's Disease
• Dementia
• Mixed Dementia
• Weight Loss

Intervention

Drug:
• mirtazapine
30 mg at bedtime

Locations

Country	Name	City	State
Belgium	CHU Brugmann	Brussels

Sponsors (1)

Lead Sponsor	Collaborator
Brugmann University Hospital

Country where clinical trial is conducted

Belgium, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	body weight		6 months	No