SPECT/CT in the Diagnosis of Dementia

Dementia Clinical Trial

— DEMSPET  

Official title:

SPECT/CT in the Diagnosis of Dementia

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01112501
• Other study ID #: KUH5031339
• Status: Completed
• Phase: N/A
• First received: April 27, 2010
• Last updated: April 27, 2010
• Start date: September 2006
• Est. completion date: January 2010

Study information

• Verified date: April 2010
• Source: Kuopio University Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Finland: Research Ethics Committee, Hospital District of Northern Savo, Finland
• Study type: Observational

Clinical Trial Summary

Aim of the study is to evaluate whether Tc-99m-ECD-SPECT/CT enhances early diagnosis of dementia in two specific patient groups: (1) patient with mild cognitive impairment, and (2) patient with possible symptoms and signs of frontotemporal dementia. Evaluation of SPECT/CT data is performed both by visual and quantitative voxel-based analyses (Statistical Parametric Mapping). The final diagnosis is based on up to four years clinical follow-up.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 82
• Est. completion date: January 2010
• Est. primary completion date: January 2010
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: N/A and older

Eligibility

Inclusion Criteria (one of these):

• healthy control

• mild cognitive impairment (recruited from a population based data)

• clinically suspected frontotemporal dementia (unset diagnosis)

Exclusion Criteria:

• unable to be scanned with SPECT/CT

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• Dementia

Locations

Country	Name	City	State
Finland	Kuopio University Hospital	Kuopio

Sponsors (2)

Lead Sponsor	Collaborator
Kuopio University Hospital	University of Eastern Finland

Country where clinical trial is conducted

Finland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Final diagnosis	(1) controls, (2) stable mild cognitive impairment (MCI), (3)MCI converted to Alzheimers's disease (AD), (4) frontotemporal dementia (FTD), suspected FTD converted to AD, (5) other final diagnoses	4 years	No