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Memantine for Agitation in Dementia — MAGD  

DEMENTIA Clinical Trial

Official title:
Pragmatic Randomized Control Trial of Memantine For Agitation In Dementia

Clinical Trial Summary

We plan to evaluate the use of memantine in Alzheimer's disease to control agitation in the acute situation i.e under 12 weeks

Clinical Trial Description

Agitation is a cause of morbidity and mortality in Alzheimer's due to distress and use of medication with side effects. Memantine has beed shown to be associated with less agitation and a recent study by forrest pharmaceuticals failed to recruit. We will perform a 12 week rct in 164 patients to test this hypothesis in a locality with no competing studies and in a clinical setting where the drug is not often used. We will compare with placebo and also use a rescue protocol derived from international best practice. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00371059
Study type Interventional
Source East Kent Hospitals University NHS Foundation Trust
Contact
Status Completed
Phase Phase 4
Start date September 2007
Completion date September 2009
View Details
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