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Clinical Trial Summary

The purpose of this clinical trial is to test whether or not the medication amantadine is effective in reducing behavioral disturbances in patients with frontotemporal dementia.


Clinical Trial Description

Behavioral disturbances are a major cause of morbidity in frontotemporal dementia (FTD), yet little is known about the effectiveness of medications to treat these disturbances. Preliminary data suggests that the dopaminergic agent amantadine may reduce these disturbances. This 6-week, prospective, randomized, placebo-controlled trial will compare amantadine to placebo to assess its effectiveness in reducing behavioral symptoms. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT00127114
Study type Interventional
Source Johns Hopkins University
Contact
Status Withdrawn
Phase Phase 4
Start date September 2005
Completion date July 26, 2007

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