Analyses of Cerebrospinalfluid in Patients With Delirium

Status Recruiting

Clinical Trial Summary

The current project aims to measure biomarkers in the cerebrospinalfluid (CSF) and serum samples from patients with delirium. We hope to uncover new insights into the pathophysiology of delirium and explore its link to dementia.

Clinical Trial Description

Delirium is a common and serious complication to acute illness, and is characterized by acute disturbances in attention, awareness, and cognition. Dementia is a major risk factor of delirium, and delirium increases the risk of dementia progression and development. As the conditions share both clinical and epidemiological features, some researchers suggest that also pathophysiological links are shared. Understanding delirium pathophysiology, which is poorly understood, may thus help elucidate early molecular mechanisms in dementia. This study aims to to increase our understanding of the pathophysiology of delirium and molecular links between delirium and dementia, by exploring cerebrospinal fluid (CSF) biomarkers. ;

Study Design

Related Conditions & MeSH terms

Delirium

Clinical Trial Details

NCT number	NCT05060614
Study type	Observational
Source	Oslo University Hospital
Contact	Leiv O Watne, PhD
Phone	40203712
Email	l.o.watne@gmail.com
Status	Recruiting
Phase
Start date	September 1, 2016
Completion date	December 30, 2027

View Details

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