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Dehydration clinical trials

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NCT ID: NCT03290638 Completed - Ridge Deficiency Clinical Trials

Comparison of Dehydrated Human Amnion-Chorion and Type 1 Bovine Collagen Membranes for Guided Bone Regeneration

GBR
Start date: October 3, 2013
Phase: N/A
Study type: Interventional

The objective of this randomized clinical study was to evaluate the use of dehydrated human amnion-chorion membrane as an exposed barrier for guided bone regeneration (GBR) after tooth extraction and to determine whether intentional exposure of this membrane to the oral environment compromises ridge dimensions and bone vitality for implant placement.

NCT ID: NCT03263975 Completed - Clinical trials for Dehydration Hypertonic

Effects of Dehydration on Neuromuscular Performance and Sympathetic Control of Cardiovascular Function

Start date: October 31, 2014
Phase: N/A
Study type: Interventional

The mechanism(s) by which dehydration (both intra- and extracellular) impairs performance are still poorly described. A loss of volume results in increased occurrence of orthostatic intolerance, including dizziness, fatigue, headaches and related symptoms with upright posture. Any of these symptoms can contribute to decreased performance in maneuvers performed in the upright posture, which includes many military tasks. Thus, loss of volume challenges the cardiovascular and blood pressure responses to systemic whole body endurance exercise, while osmolality is the stimulus for intracellular dehydration that may impair local muscle force production by impairing contractile function, neural signaling, or both. In this study, we will compare how both types of dehydration affect MSNA and CAC. The results of this study will provide mechanistic insight for how dehydration (intra- or extracellular) impairs systemic whole body and local small muscle performance in vivo. This Basic Science study seeks to understand how volume and osmolality impact MSNA and CAC as a basis for improving potential countermeasures, such as a more optimally formulated rehydration beverage. Therefore, this study directly complements Task Area T10 (Hot Weather Operations and Hydration: Injury and Performance Optimization) and impacts virtually all 14 Military Operational Medicine Research Program Drivers.

NCT ID: NCT03229109 Completed - Dehydration Clinical Trials

Analysis of Sweat Secretion and Body Dehydration Monitoring

Start date: May 3, 2017
Phase: N/A
Study type: Interventional

Monitoring of a person's physical status is a key point for maintaining of "healthy life". Wearable devices provide a unique possibility for real-time monitoring. This study aims to estimate the accuracy of Spectrophon Dehydration Body Monitor (DBM) incorporated in smartwatch Samsung Gear S2 and sport band Samsung Gear Fit2 by comparing data obtained by DBM with the total weight lost during exertion.

NCT ID: NCT03123601 Completed - Clinical trials for Nursing Home Residents

Feasibility of Risk Sign Displays to Prevent Falls, Dehydration and Pulmonary Aspiration in Nursing Homes

Start date: November 1, 2016
Phase: N/A
Study type: Interventional

BACKGROUND: Prior research has shown a relationship between dehydration, falls and pulmonary aspiration among older adults in nursing and health care facilities, which contributes to its loss of independence and quality-of-life. Is believed that improving communication among health professional decreases the number of adverse events in institutionalized patients. This study will evaluate the feasibility of a set of sign displays designed to communicate fall, dehydration and pulmonary aspiration risks and will reflect on tailored interventions to manage these events in nursing homes. METHODS AND ANALYSIS: This will be a national, single-center, feasibility study. All patients, with chronic neurologic diseases selected from a nursing home, will be invited to participate. At baseline patients will undertake a screening risk assessment and it will be attributed a correspondent risk display. Study duration will be a minimum of 3 months per participant, including daily record of events and monthly interview assessments. Events data will be compared with historical data extracted retrospectively from medical and nursing charts.

NCT ID: NCT03021109 Completed - Dehydration Clinical Trials

Assessment of Volume Status by Bedside Ultrasound in Children With Acute Gastroenteritis

Start date: December 2016
Phase: N/A
Study type: Interventional

The purpose of the study is assessment of volume status by bedside ultrasound in children with acute gastroenteritis

NCT ID: NCT02980939 Completed - Dehydration Clinical Trials

The Role of Hydration on Exercise Performance - ODIN

ODIN
Start date: November 2016
Phase: N/A
Study type: Interventional

During exercise in the heat, there is a need to replenish fluids in order to avoid dehydration and decrease the risk for heat illness. What drives this urge to drink is the thirst mechanism. Following ingestion of fluids, there is an inhibition of thirst before there is a replenishing of fluids. However, there is little scientific evidence of where thirst is inhibited, if this thirst inhibition is augmented by exercise and how thirst itself influence exercise performance. Further, during rehydration studies, it is very difficult to successfully blind a subject to their drinking/hydration protocol. Previous studies that have blinded a subject to their drinking have used various methods such as intravenous fluid administration and/or nasogastric tubes. Therefore, the purpose of this research is to examine the mechanistic roles thirst inhibition plays while exercising in the heat while undergoing intravenous fluid administration. Specific attention will be directed to the cardiovascular and thermoregulatory function of the individuals. All blood, cardiovascular, thermoregulatory, and perceptual measures are shown in the diagram below.

NCT ID: NCT02963753 Completed - Clinical trials for Gestational Diabetes

Hyperemesis Gravidarum and 75 Gram Oral Glucose Tolerance Test

Start date: January 2016
Phase: N/A
Study type: Observational

Hyperemesis gravidarum (HEG) is not only nausea and vomiting of pregnancy, but it is also a clinical syndrome including endocrine and metabolic complications. Recently, some investigators have been begun performing researches related to the development of gestational diabetes mellitus (GDM) in pregnant women with HEG because they think about those metabolic and endocrine complications of HEG.In the literature there are few studies assessing how HEG has effects on GDM or 75 gram oral glucose tolerance test (OGTT). So the investigators aim to evaluate the effects of HEG on 75 gram OGTT.

NCT ID: NCT02960789 Completed - Dehydration Clinical Trials

Hydration Status Evaluation of Dehydrated Children With Experimental Devices

Start date: November 2016
Phase: N/A
Study type: Interventional

A pediatric study in collaboration with Boston Children's Hospital to review the performance of two novel hydration status measurement devices against standard clinical assessment methods, through repeated measurement of hydration status of dehydrated children admitted to the emergency department receiving rehydration therapy, followed by an at-home follow-up measurement once symptoms have resolved.

NCT ID: NCT02926989 Completed - Dehydration Clinical Trials

Intravenous Fluids in Hospitalised Children

Start date: October 3, 2016
Phase: Phase 4
Study type: Interventional

The main objective of the trial is to evaluate the risk of hypokalemia following administration of a isotonic solution compared to a hypotonic solution in acutely ill hospitalised children, who need intravenous fluid therapy.

NCT ID: NCT02870491 Completed - Diarrhea Clinical Trials

Working With Community Health Workers to Increase ORS Use in Uganda

Start date: August 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to assess how free distribution and preemptive home delivery of oral rehydration salts (ORS) by community health workers affects ORS use. The investigators will measure the impact of the combination of the two interventions (free distribution + pre-emptive home delivery) as well as the impact of each intervention separately (free distribution without home delivery and pre-emptive home delivery without free distribution).