Deficiency, Vitamin D Clinical Trial
Official title:
Effect of Vitamin D Replacement on Bone Healing in Mini-dental Implants: a Randomized Clinical Trial
1. Title
2. Executive team
3. Research line
4. Summary
5. Research problem
6. Justification
7. Literature review
8. Objectives
9. Materials and methods
10. Dissemination of knowledge generated
11. Schedule of activities
12. Budget
13. References
14. Annexes
Status | Recruiting |
Enrollment | 20 |
Est. completion date | April 30, 2018 |
Est. primary completion date | December 30, 2017 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 25 Years to 75 Years |
Eligibility |
Inclusion Criteria: - Patients of both sexes; - No medical, temporary or intra-oral contraindications; - Good general health; - Need of implant in the maxilla in the posterior region (with a minimum of 5 mm of bone height visualized radiographically) or in mandible in posterior region; - With vitamin D deficiency / deficiency (considering serum level of = 15 ng / ml at = 25 ng / ml). Exclusion Criteria: - Medical, temporary or intrabuccal contraindications; - Smokers; - Use of corticoid; - Post-operative of bariatric surgery; - Bone height less than 5mm; - Need for maxillary sinus lift; - Vitamin supplementation D. |
Country | Name | City | State |
---|---|---|---|
Brazil | Isadora Rinaldi | Rondinha | Rio Grande Do Sul |
Lead Sponsor | Collaborator |
---|---|
Universidade de Passo Fundo |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Percentage of bone implant contact | Histomorphometry will be used as a method of analysis. It will evaluate the initial stage of osseointegration in the two groups, relating it to insufficiency / deficiency and sufficiency of vitamin D. The percentage of bone implant contact, defined as the amount of mineralized bone in direct contact with the surface of the miniimplant, will be evaluated. | 2 months | |
Secondary | Serum levels of vitamin D (ng/ml) | The 25-hydroxyvitamin D test is a common blood test and is the best way to monitor vitamin D levels. The test can determine if the person's blood has deficiency or excessive vitamin D. The method used to evaluate the blood test is chemiluminescent immunoassay technology (CLIA). | 2 months |
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