Effect of Vitamin D Replacement on Bone Healing in Mini-dental Implants

Deficiency, Vitamin D Clinical Trial

Official title: Effect of Vitamin D Replacement on Bone Healing in Mini-dental Implants: a Randomized Clinical Trial

Status Recruiting

Clinical Trial Summary

1. Title

2. Executive team

3. Research line

4. Summary

5. Research problem

6. Justification

7. Literature review

8. Objectives

9. Materials and methods

10. Dissemination of knowledge generated

11. Schedule of activities

12. Budget

13. References

14. Annexes

Clinical Trial Description

This is a clinical research study, characterized by a randomized, double-blind, placebo-controlled clinical trial. Background: Vitamin D replacement could aid in the osseointegration of dental implants. Objective: to evaluate the effect of vitamin D replacement on osseointegration of dental implants in humans. Materials and methods: Twenty individuals with hypovitaminosis D underwent dental miniimplants and randomized to two equal groups for treatment with vitamin D (5000 IU / day) or placebo for 2 months. After two months, the miniimplants will be removed and prepared for histomorphometric analysis, which will evaluate bone implant contact in percentage. Testing the hypothesis that the contact between bone and implant and the bone density in the threaded area in the test group is higher than in the control group. Test t will be used to compare the differences between the groups. ;

Related Conditions & MeSH terms

• Avitaminosis
• Deficiency, Vitamin D
• Vitamin D Deficiency

• NCT number: NCT03356730
• Study type: Interventional
• Source: Universidade de Passo Fundo
• Contact: Isadora Rinaldi
• Phone: (54) 9 9696-8365
• Email: 120910@upf.br
• Status: Recruiting
• Phase: Phase 1
• Start date: November 19, 2017
• Completion date: April 30, 2018