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Clinical Trial Summary

The primary objective is to evaluate whether apixaban is more effective in treating patients with isolated calf vein thrombosis (DVT) than serial imaging of the DVT for preventing thrombus spread, pulmonary embolism (PE) and/or recurring DVTs.


Clinical Trial Description

This is a randomized double-blind placebo controlled superiority clinical trial. Patients will be identified at the time of the diagnosis of acute calf deep vein thrombosis and approached at that time. If they agree they would be randomly assigned to placebo or apixaban treatment for three months. Along with this they will also undergo repeat ultrasounds at 7, 14, and 90 days along with telephone follow-up at 30 and 60 days. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03590743
Study type Interventional
Source Mayo Clinic
Contact
Status Terminated
Phase Phase 4
Start date February 19, 2019
Completion date June 3, 2019

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