Calf Deep Vein Thrombosis Treatment Trial

Status Terminated

Clinical Trial Summary

The primary objective is to evaluate whether apixaban is more effective in treating patients with isolated calf vein thrombosis (DVT) than serial imaging of the DVT for preventing thrombus spread, pulmonary embolism (PE) and/or recurring DVTs.

Clinical Trial Description

This is a randomized double-blind placebo controlled superiority clinical trial. Patients will be identified at the time of the diagnosis of acute calf deep vein thrombosis and approached at that time. If they agree they would be randomly assigned to placebo or apixaban treatment for three months. Along with this they will also undergo repeat ultrasounds at 7, 14, and 90 days along with telephone follow-up at 30 and 60 days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03590743
Study type	Interventional
Source	Mayo Clinic
Contact
Status	Terminated
Phase	Phase 4
Start date	February 19, 2019
Completion date	June 3, 2019

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05003843` - BOLT: Study of the Indigo® Aspiration System When Used in Patients With Deep Vein Thrombosis	N/A
Recruiting	`NCT03937947` - Traumatic Brain Injury Associated Radiological DVT Incidence and Significance Study
Withdrawn	`NCT04136561` - Novel Strategy to Encourage Early Removal of Central Venous Catheters	N/A
Completed	`NCT03420625` - Blood Flow Stimulation in the Lower Limbs by Application of Different External Devices	N/A
Recruiting	`NCT02507180` - Safely Ruling Out Deep Vein Thrombosis in Pregnancy With the LEFt Clinical Decision Rule and D-Dimer
Completed	`NCT02555111` - Xarelto Versus no Treatment for the Prevention of Recurrent Thrombosis in Patients With Chronic Portal Vein Thrombosis.	Phase 3
Terminated	`NCT02469376` - Evaluation of a New Imagingtechnologie for Thrombosis	Phase 1
Completed	`NCT01975090` - The SENTRY Clinical Study	N/A
Completed	`NCT02037607` - Incidence of Venous Thromboembolism in Children Undergoing Elective Neurosurgical Procedures	N/A
Not yet recruiting	`NCT01357941` - Need for Antepartum Thromboprophylaxis in Pregnant Women With One Prior Episode of Venous Thromboembolism (VTE)	N/A
Completed	`NCT00773448` - Screening for Occult Malignancy in Patients With Idiopathic Venous Thromboembolism	N/A
Completed	`NCT00771303` - Ruling Out Pulmonary Embolism During Pregnancy:a Multicenter Outcome Study
Completed	`NCT00720915` - D-dimer to Select Patients With First Unprovoked Venous Thromboembolism Who Can Have Anticoagulants Stopped at 3 Months	N/A
Completed	`NCT00244725` - Odiparcil For The Prevention Of Venous Thromboembolism	Phase 2
Completed	`NCT00264277` - D-dimer to Establish Duration of Anticoagulation After Venous Thromboembolism	Phase 4
Completed	`NCT00365950` - 3 Months' Versus 6 Months' Anticoagulation in Patients With DVT and/or PE	Phase 4
Completed	`NCT00182403` - Fixed Dose Heparin Study	Phase 3
Completed	`NCT03682419` - Evaluation of Precision and Accuracy of INR Measurements in a Point of Care Device (OPTIMAL)	N/A
Not yet recruiting	`NCT04981327` - The API-CALF Study: Apixaban to Treat Calf Vein Thrombosis	Phase 3
Recruiting	`NCT03240120` - A Study of Dabigatran Etexilate as Primary Treatment of Malignancy Associated Venous Thromboembolism	Phase 3