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Effects Of Different Anesthesia Applications On Mood, Depression, And Anxiety Levels In Burn Patients

Deep Sedation Clinical Trial

Official title:
Effects Of Different Anesthesia Applications On Mood, Depression, And Anxiety Levels In Burn Patients

Clinical Trial Summary

Adequate and effective pain management and prevention of depression are essential in burn patients. This study aims to investigate the effects of ketamine sedation in burn patients in terms of mood disorders, depression, anxiety, and suicidal tendency during intensive care follow-up in the postoperative period.

Clinical Trial Description

Aim: Adequate and effective pain management and prevention of depression are essential in burn patients. This study aims to investigate the effects of ketamine sedation in burn patients in terms of mood disorders, depression, anxiety, and suicidal tendency during intensive care follow-up in the postoperative period. Methods: The study was conducted with 67 patients between 18 and 65 years of age, who were ASA I-II class, had basic communication skills, no previous diagnosis of psychiatric illness, and no history of neuropsychiatric or cognitive disease or related treatment. After preoxygenation, anesthesia induction was performed with 2 mg/kg IV propofol and 1 mcg/kg IV fentanyl in the general anesthesia group. Anesthesia was continued with a mixture of 0.3-0.5 mcg/kg/min remifentanil, 2% sevoflurane, 50% air, 50% oxygen. In the sedation group, 1 mcg/kg IV fentanyl and 1 mg/kg IV ketamine were administered at induction; anesthesia was maintained by adding 30-50 mg IV propofol if necessary. The Montgomery-Asberg Depression Rating Scale (MADRS), the Hamilton Anxiety Rating Scale (HAM-A), and the Beck Scale for Suicide Ideation (BSSI) were administered preoperatively and on postoperative day one by the psychiatrist. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06165848
Study type Observational [Patient Registry]
Source T.C. Saglik Bakanligi Ankara Bilkent Sehir Hastanesi
Contact
Status Completed
Phase
Start date July 9, 2020
Completion date June 7, 2021
View Details
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