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Decompression Sickness clinical trials

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NCT ID: NCT04895501 Completed - Runners Clinical Trials

Effects of Shoe Longitudinal Bending Stiffness

FAT-FLEX
Start date: February 7, 2022
Phase: N/A
Study type: Interventional

Carbon plates inserted in competitive running shoes have been increasingly used in the past 2-3 years and several investigations have shown that these plates increase the longitudinal bending stiffness (LBS) of the shoe. It leads to a redistribution of muscle work and to a modification of the force generation conditions, which may reduce the energy cost of running (Cr) and improve performance.

NCT ID: NCT04459481 Completed - Clinical trials for Intubation;Difficult

Comparison of Two Bending Angles for Nasotracheal Intubation With a Malleable Vedio Stylet

Start date: June 4, 2020
Phase: N/A
Study type: Interventional

Video intubating stylet can be safely and effectively used for nasotracheal intubation, but the optimal bending angle is still unknown. In this study, the optimal bending angle will be determined by comparing the intubation time and success rate of nasotracheal intubation with video intubating stylet at two different bending angles.

NCT ID: NCT03693235 Completed - Tracheal Intubation Clinical Trials

Adequate Bending Angle of a Lightwand

Start date: November 14, 2018
Phase: N/A
Study type: Interventional

For tracheal intubation with a lightwand, adequate bending angle was not exactly investigated. The purpose of the study is compare three bending angles of lightwands for safe and efficient tracheal intubation.

NCT ID: NCT03390335 Completed - Clinical trials for Acute Mountain Sickness

Decompression Tables for Diving at Altitude

Start date: February 13, 2018
Phase: N/A
Study type: Interventional

The aims of this proposal are to test current USN procedures for adjusting decompression procedures during air diving at 8,000 and 10,000 ft altitude and to provide a decompression algorithm for no-stop dives to 100 feet of sea water (fsw) at 10,000 and 12,000 ft altitude using enriched O2 (PO2=1.3 ATM). Additionally, the experiments will determine whether a period of hyperbaric hyperoxia, such as would be experienced during a dive at altitude, reverses altitude acclimatization, resulting in a return of acute mountain sickness (AMS) symptoms.

NCT ID: NCT02736006 Completed - Clinical trials for Decompression Sickness

Decreases in Diffusing Lung Capacity for Carbon Monoxide (DLCO) in Occupational Divers and Their Impact on Decompression Sickness Risks

DACODEC
Start date: March 22, 2016
Phase: N/A
Study type: Interventional

Diving disorders and particularly Decompression sickness (DCS) represent a major concern in recreational and occupational pressure-related activities. As a result of decompression from higher to lower ambient pressure bubbles which are formed in vascular flow and in tissues take part in embolism then resulting in DCS. Individual factors such as vascular or respiratory defects are now considered to increase the risk of this dysbarism disease.

NCT ID: NCT02468752 Completed - Inflammation Clinical Trials

Reduction of Venous Emboli Load After Breathing Normobaric Oxygen Compared to Air

Start date: May 2015
Phase: Phase 2/Phase 3
Study type: Interventional

Primary objective: - Assessment of venous gas emboli load post diving when breathing normobaric oxygen compared to air. Secondary objective: - Assessment of fluid markers of central nervous system injury in blood post diving - Assessment of fluid markers of inflammation and endothelial dysfunction in blood post diving Tertiary objective: - Assessment of DCS frequency

NCT ID: NCT02432131 Completed - Clinical trials for Foramen Ovale, Patent

Decompression Sickness in Divers With or Without Patent Foramen Ovale

DIVER-PFO
Start date: May 2015
Phase:
Study type: Observational [Patient Registry]

The investigators will prospectively estimate incidences of decompression sickness in SCUBA divers with or without patent foramen ovale (PFO). All participants will receive transesophageal echocardiogram and transcranial doppler to ascertain whether they get a PFO. Clinical follow up will be undertaken 3 month after transesophageal echocardiographic evaluation, and every 6 month up to 3 years by E-mailing or telephone interview with self-questionnaire report. All decompression sickness (DC) events or DC-like symptoms will be reviewed by a professional diver, who is a medical doctor and member of DAN-AP, and a neurologist.

NCT ID: NCT02243345 Completed - Clinical trials for Recompression Treatment After Decompression Sickness

Delayed Recompression for Decompression Sickness

Start date: September 2013
Phase: N/A
Study type: Observational

Decompression sickness syndrome (DCS) is caused by microbubbles forming in blood vessels or tissues during a reduction in environmental pressure (decompression). Bubbles have mechanical, embolic and biochemical effects with manifestations ranging from none to fatal. By reducing bubble volume and hastening inert gas elimination, recompression therapy with hyperbaric treatment remains the main therapy for DCS. The most common hyperbaric protocol used, is based on US Navy Treatment table 6, started as early as possible after surfacing. The outcome of hyperbaric therapy varies with reported complete resolution in 13%-63% of the patients suffering from severe DCS, and in 73%-100% of the patients with mild-moderate DCS. The significance of time to recompression is controversial. It has been suggested that early hyperbaric treatment improves the outcome by decreasing bubble size and avoiding further tissue injury. However, in recent studies time to recompression had very little effect on clinical recovery. Moreover, the time beyond which hyperbaric treatment isn't effective has not been determined yet. The aim of this study was to evaluate the clinical outcome of delayed hyperbaric treatment to divers who referred to tertiary care hospital hyperbaric unit, more than 48 hours after surfacing. The clinical outcome of the delayed hyperbaric treatments was compared to early treatments given at the same hyperbaric unit.

NCT ID: NCT02118207 Completed - Clinical trials for Endothelial Dysfunction

Exercise and Repetitive Diving

Start date: October 2013
Phase: N/A
Study type: Interventional

SCUBA diving frequently involves repetitive exposures over multiple days. The goal of this study was to see how exercise impacts microparticles (MPs), endothelial function, and venous gas emboli (VGE) over a series of dives. 16 divers in 2 groups each completed 6 dives. One group completed 3 control dives followed by 5 days rest then 3 dives preceded by exercise. The other group completed the opposite protocol. Flow-mediated dilation (FMD) data and blood for MP analysis was collected before and after each dive. VGE were monitored via transthoracic echocardiography 30, 60, and 90 min after surfacing. Exercise before diving consisted of 60 min running outdoors including 8x4 min intervals at 90% VO2max effort.

NCT ID: NCT02064361 Completed - Clinical trials for Decompression Sickness

High Intensity Cycling Before SCUBA Diving Reduces Post-decompression Microparticle Production and Neutrophil Activation

Start date: February 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the impact of high intensity,anaerobic exercise, in the form of cycling, on SCUBA diving. Outcomes are determined by the quantification and subtype of circulating microparticles, complete blood counts, and the quantification of venous gas emboli, measured via transthoracic echocardiography, in the cardiac cavities.