Autoimmune Cytopenias as a Sign of Primary Immunodeficiency.

Status Active, not recruiting

Clinical Trial Summary

Autoimmune cytopenias resistant to treatment are among the most common clinical manifestations observed in patients with congenital alterations of the immune system, such as primary immunodeficiencies (PI). The exact contribution of immune system alterations to the pathogenesis of autoimmune cytopenias has not yet been fully elucidated. Moreover, conventionally employed therapeutic strategies often fail, leading to increased healthcare costs, high morbidity, and even mortality. Therefore, there is a need to establish clinical guidelines for diagnosis and to identify early biomarkers capable of identifying individuals responsive to therapy. Thus, a systematic approach to the study of such pathologies will allow for the identification of early biomarkers and facilitate the development of targeted therapeutic strategies

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Anemia
Cytopenia
Leukopenia
Primary Immunodeficiency Diseases
Thrombocytopenia

Clinical Trial Details

NCT number	NCT06276036
Study type	Interventional
Source	Meyer Children's Hospital IRCCS
Contact
Status	Active, not recruiting
Phase	N/A
Start date	July 23, 2019
Completion date	June 1, 2025

View Details

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