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Cysts clinical trials

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NCT ID: NCT04363151 Completed - Clinical trials for Patients Who Underwent Surgury for Hydatid Cyst

The Current Study Aimed to Evaluate the Therapeutic Features and Complications of Liver Hydatid Cyst in Patients Who Underwent Surgery for CE in Fars Province, Southern Iran.

Start date: January 15, 2004
Phase:
Study type: Observational

The current study aimed to evaluate the therapeutic features and complications of liver hydatid cyst in patients who underwent surgery for CE in Fars province, southern Iran. A total of 293 patients who underwent surgery for liver hydatid cyst from 2004 to 2018 in Fars Province, southern Iran, were retrospectively evaluated. The clinical records of patients were reviewed and the demographic and clinical characteristics of each patient were assessed.

NCT ID: NCT04244422 Completed - RADICULAR CYSTS Clinical Trials

Radicular Cyst Enucleation Using Piezosurgery Versus Conventional Surgery

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

AIM: The study was intended to evaluate the effectiveness of piezosurgery in enucleation of radicular odontogenic cysts in comparison to the conventional technique from both the clinical and radiographic perspectives.

NCT ID: NCT04079764 Completed - Renal Cyst Clinical Trials

Surveillance of Complex Renal Cysts - the SOCRATIC Pilot Study

SOCRATICp
Start date: September 30, 2019
Phase:
Study type: Observational

One third of individuals aged >60 years will be diagnosed with at least one renal cyst following abdominal imaging. These cystic lesions are categorized according to the Bosniak classification which categorizes cysts according to their degree of complexity and risk of malignancy. Growing evidence suggests that a significant proportion of Bosniak III and IV cysts are benign and that the malignant ones present low metastatic potential. Since renal surgery carries substantial morbidity (20%) and potential mortality (0.5%), active surveillance has gained attention as a potential tradeoff to surgery to overcome overtreatment. Therefore, prospective studies of long-term follow-up are needed to confirm the oncologic outcomes of this strategy for Bosniak III/IV cysts. We first designed a pilot study that will assess the feasibility of a subsequent larger multicenter observational study aiming to ascertain mid-term safety of active surveillance. The objectives of this pilot study are a) Determining patients and urologists buy-in and barriers to the proposed intervention; b) Collecting perceptions and concerns of patients and urologists; c)

NCT ID: NCT03975712 Completed - Rathke's Cleft Cyst Clinical Trials

Evaluation of the Pravalence of Rathke's Cleft Cyst of Children Under 15 Years

PREVA-KPR
Start date: November 1, 2017
Phase:
Study type: Observational

The goal of the study was to evaluate the pravalence of Rathke's Cleft Cyst of children under 15 years of age and demonstrate that their prevalence is higher than for patients over 15 years of age, due to their embryonic origin. It is also aimed to describe their aspect on MRI and evaluate the interobserver agreement in the detection of Rathke's Cleft Cyst.

NCT ID: NCT03927651 Completed - Endometriosis Clinical Trials

ICG to Assess Ovarian Perfusion

Start date: June 1, 2019
Phase: Early Phase 1
Study type: Interventional

To assess the feasibility of using intravenous ICG to characterize the vascular perfusion of ovaries during gynecologic surgery

NCT ID: NCT03820531 Completed - Pancreas Cyst Clinical Trials

DNA-mutation Analysis in Cyst Fluid of Suspected Intraductal Papillary Mucinous Neoplasia of the Pancreas

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Diagnostic tools are needed to identify mucinous cysts for further evaluation or follow-up respectively to identify cysts with HGD or invasive cancer at an early stage for surgical resection. Molecular genetic analysis of pancreatic cyst fluid is a new but rapidly evolving method to identify KRAS/GNAS oncogenic driver mutations in mucinous cysts and to identify tumour suppressor gene mutations which are involved in advanced cysts with HGD or carcinoma. The ongoing ZYSTEUS-study tries to implement DNA mutation analysis by Next Generation Sequencing in the diagnostic algorithm of pancreas cyst evaluation. The first aim is to distinguish mucinous from non-mucinous cysts. The second aim is to define relevant tumour suppressor gene mutations which are relevant to distinguish between LGD and HGD/carcinoma in mucinous cysts.

NCT ID: NCT03771833 Completed - Clinical trials for Breast Cancer Female

M5 vs. M6 Comparison Study With a Sub Study Into the Dielectric Constant of Aspirated Cyst Fluid

Start date: February 19, 2019
Phase: N/A
Study type: Interventional

The MARIA breast imaging system is a Conformité Européenne (CE)-marked radio-frequency (RF) medical imaging device. The system employs an electromagnetic imaging technique that exploits the dielectric contrast between normal and cancerous tissues. The performance and imaging characteristic differences between the M5 and M6 versions of MARIA are not yet well demonstrated in the clinical environment, particularly with regards to cysts. The evaluation of some aspects of this potentially important new technology will occur in this comparative technical study. Further, the dielectric constant of cyst fluid is currently not well understood and obtaining readings from aspirated cyst fluid in applicable patients will be attempted.

NCT ID: NCT03740360 Completed - Pancreatic Cyst Clinical Trials

Contrast Enhanced Ultrasound and Molecular Analysis in the Diagnosis of Pancreatic Cyst

Start date: June 1, 2017
Phase:
Study type: Observational [Patient Registry]

This study evaluates the use of contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) and cyst fluid molecular analysis in the differential diagnosis of pancreatic cysts and the detection of malignancy.

NCT ID: NCT03578445 Completed - Clinical trials for Pancreatic Adenocarcinoma

Utility of EUS-guided Microbiopsies in Pancreatic Cystic Lesions

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine clinical impact of EUS-guided microbiopsy procedure and supplementary molecular analyses compared to standard diagnostic workup of pancreatic cysts. The hypothesis is that a combination of previously mentioned modalities may change the management of some pancreatic cystic lesions, increase the diagnostic accuracy and optimize the discrimination between high- and low-risk pancreatic cysts.

NCT ID: NCT03415477 Completed - Recurrent Disease Clinical Trials

Denosumab: A Potential Treatment Option for Aneurysmal Bone Cysts

Deno-ABC
Start date: January 1, 2014
Phase: Phase 1/Phase 2
Study type: Interventional

The efficacy of traditional therapeutic approaches for aneurysmal bone cysts (ABC), such as surgery, embolization, sclerotherapy and radiotherapy, are often compromised for lesions in axial skeletons and adolescents complicated with pathological fracture. Therefore, denosumab, a new drug that has been successfully used in giant cell tumor of bone but has seldom used in ABC, was used to treat ABC in this trial.