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Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis

Cystic Fibrosis Clinical Trial

Official title:
Pilot Study of Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis

Clinical Trial Summary

This is a small pilot study with the goal of identifying a superior sputum collection method in Cystic Fibrosis patients unable to produce a sputum. Participants will use the Volara System during clinic visit in an attempt to produce sputum.

Clinical Trial Description

Since the introduction of CFTR modulator therapies, most patients with Cystic Fibrosis (CF) have been unable to produce an adequate sputum sample for clinical monitoring. COVID-19 also presented a safety concern for staff and patients that may become exposed during sputum induction performed in the clinic rooms due to lack of negative pressure rooms and especially for patients who were unvaccinated. These issues led to lack of microbiology data for clinical care. The purpose of this project is to identify a superior sputum collection method for those patients unable to produce a sputum to guide future antimicrobial management. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06311292
Study type Interventional
Source University of Pittsburgh
Contact Daniel Weiner, MD
Phone 412-692-8097
Email Daniel.Weiner@chp.edu
Status Recruiting
Phase N/A
Start date May 29, 2024
Completion date June 2025
View Details
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