Evaluation of Salt Status in Patients With Cystic Fibrosis

Status Completed

Clinical Trial Summary

The results of the annual check-up will be collected to evaluate the best urinary marker for fractional sodium excretion and salt status will be correlated to clinical outcome measures.

Clinical Trial Description

Patients with cystic fibrosis need extra salt as they have increased losses through sweat. Current advices are to follow and supplement if needed, however the way to follow salt depletion is unclear. The best way is to calculate fractional salt excretion. This needs a simultaneous blood and urine sample for electrolytes and creatinin. Urinary surrogate markers have been validated on only 10 patients. At the annual check-up patients with cystic fibrosis receive these measurements. The investigators will collect the measurements and calculate fractional excretion and the possible surrogate markers on urine. Further this will be correlated to nutritional and pulmonary status and patient subgroups at risk will be identified. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04556162
Study type	Observational
Source	University Hospital, Ghent
Contact
Status	Completed
Phase
Start date	January 1, 2018
Completion date	November 21, 2021

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