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Vitamin K Supplementation to Reduce Deficiencies in Adults With Cystic Fibrosis — VITK-FK  

Cystic Fibrosis Clinical Trial

Official title:
Vitamin K Supplementation to Reduce Deficiencies in Adults With Cystic Fibrosis : A Pilot Study

Clinical Trial Summary

Cystic fibrosis (CF) patients are at risk for vitamin K deficiencies. Supplementation for fat-soluble vitamins A, D, and E is well established, but in CF, there is little data for vitamin K concerning the optimal dose and frequency of supplementation. Beyond its known role in coagulation, research has highlighted the role of vitamin K for bone health and the control of blood sugar levels. However, after pulmonary complications, the risk of diabetes and bone diseases are two important and frequent complications of CF. Patients with CF being at risk of vitamin K deficiencies, this vitamin could play a role in these complications.

Clinical Trial Description

The investigators propose a pilot study (carried out to assess its feasibility on a larger scale) to evaluate if a supplement of vitamin K improves vitamin K serum levels in CF patients by comparing: - Group A: a vitamin K supplement of 2mg, every day for 6 months - Group B: a vitamin K supplement of 7mg, twice a week for 6 months ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04496921
Study type Interventional
Source Institut de Recherches Cliniques de Montreal
Contact
Status Withdrawn
Phase N/A
Start date August 10, 2020
Completion date August 16, 2021
View Details
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