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Prediction of Survival in Children With Cystic Fibrosis Using the Multiple-breath Washout

Cystic Fibrosis Clinical Trial

Official title:
Multiple-breath Washout for Lung Function Testing in Children With Cystic Fibrosis: Predictive for Survival?

Clinical Trial Summary

Retrospective cohort study using routinely collected annual data on lung clearance index (LCI) in combination with clinical data to predict survival in patients with Cystic Fibrosis. The primary study endpoint is the association of LCI with the compound outcome survival or lung transplantation in patients with CF.

Clinical Trial Description

Retrospective analysis of longitudinal data collected during clinically routine from approximately 200 patients with CF aged 3 years or more between 01.01.1980 and 31.12.2005. The overall aim of this project is to retrospectively assess whether LCI measured for clinical purposes during school age is predictive for survival or lung transplantation in adulthood. For this, the investigators will assess in a systematic way clinically measured LCI and relate them with the compound outcome survival or lung transplantation retrospectively. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04016194
Study type Observational
Source University Hospital Inselspital, Berne
Contact
Status Completed
Phase
Start date January 1, 1990
Completion date December 2005
View Details
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