Cystic Fibrosis Clinical Trial
— MIRDIAMUCOOfficial title:
Determination of Circulating miRNAs as Diagnostic Markers of Lung Disease in Cystic Fibrosis
NCT number | NCT02992080 |
Other study ID # | 9548 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | July 12, 2016 |
Est. completion date | June 2020 |
Verified date | December 2021 |
Source | University Hospital, Montpellier |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The aim of our study is to assess miRNAs expression profiles in the circuling blood of patients with cystic fibrosis and highlight "signatures" that could reflect the pulmonary status of patients
Status | Completed |
Enrollment | 80 |
Est. completion date | June 2020 |
Est. primary completion date | June 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 12 Months to 65 Years |
Eligibility | Inclusion Criteria: - Patients with Cystic fibrosis (CF) (MIM#219700) who are compound heterozygous or homozygous for CF causing mutations Healthy controls non -smokers and free pulmonary disease Exclusion Criteria: - Participation or within the exclusion period of other clinicals trials Patients carrying mutations of clinical varying consequences or non CF-causing mutations - smokers |
Country | Name | City | State |
---|---|---|---|
France | Montpellier University Hospital | Montpellier | |
France | Necker Hospital | Paris |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Montpellier |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Comparison of miRNAs expression between Cystic Fibrosis (CF) patients and healthy controls | Compare the distributions of miRNAs expression in blood samples of CF patients and to healthy controls | After blood collection: 2 years | |
Secondary | Assesment of miRNAs expression in Cystic Fibrosis Patients depending on the pulmonary status | Compare the distributions of miRNAs expression in blood samples of CF patients with mild lung disease and CF patients with severe lung disease | After blood collection 2 years |
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