Effect of Proton Pump Inhibitors on CF Pulmonary Exacerbations

Status Completed

Clinical Trial Summary

Gastroesophageal reflux disease (GERD) is a common problem in cystic fibrosis (CF). It may lead to worsening lung function and more respiratory infections for a person with CF. This study will look at treating GERD with a medication, esomeprazole. The medication stops stomach acid from being made. The study will see if there are fewer respiratory infections and improved lung function in patients with CF when taking esomeprazole.

Clinical Trial Description

This is a randomized, placebo controlled intervention study in patients with CF who have a history of frequent exacerbations. Treatment duration is 6 months. ;

Study Design

Related Conditions & MeSH terms

Cystic Fibrosis

Clinical Trial Details

NCT number	NCT01983774
Study type	Interventional
Source	Columbia University
Contact
Status	Completed
Phase	Phase 2
Start date	February 2008
Completion date	August 2011

View Details

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