VX-770 Expanded Access Program

Status Approved for marketing

Clinical Trial Summary

The purpose of this expanded access program is to provide VX-770 prior to its commercial availability to people with cystic fibrosis (CF) who have at least one copy of the G551D-CFTR mutation and who are in critical medical need and who are not eligible for participation in other Vertex-sponsored studies.

Clinical Trial Description

VX-770, a compound being developed by Vertex Pharmaceuticals Incorporated (Vertex) for the treatment of CF, is an orally bioavailable small molecule that targets the underlying defect in CF, the dysfunctional CFTR protein. In Phase 3 studies of VX-770 in patients with CF and a G551D CFTR mutation, improvements in CFTR function (measured by reduction in sweat chloride concentration) and improvements in lung function were observed.

Patients who are interested in the VX-770 Expanded Access should contact their CF physician about participation.

Physicians interested in participating as a site should contact 800-745-4484. ;

Study Design

N/A

Related Conditions & MeSH terms

Cystic Fibrosis

Clinical Trial Details

NCT number	NCT01381289
Study type	Expanded Access
Source	Vertex Pharmaceuticals Incorporated
Contact
Status	Approved for marketing
Phase	N/A

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