Cystic Fibrosis Clinical Trial
Official title:
Cystic Fibrosis: Improvement of Muscle Force and Function by Whole Body Vibration Exercise
The purpose of this study is to evaluate the effects of whole body vibration (WBV) on muscle function in adult CF-patients.
Cystic Fibrosis (CF) is the most common chronic hereditary disease in Caucasians. Due to
improved therapy and better understanding of the disease, life expectancy has risen to an
average of 38 years and is continuing to rise. With the increased life-expectancy it becomes
even more important to maintain functional activity as part of quality of life. Mechanical
stimulation in form of whole body vibration (WBV) is a new type of exercise currently tested
in sports, geriatrics and rehabilitation. It has recently been found to be a safe and
efficient method to activate muscular activity via stretch reflexes leading to improvement
of muscular performance, body balance and physical functioning.
10 patients of the CF Center Cologne, Germany, took part in the Galileo study. They were
provided by the vibrating platform (Galileo 2000)for whole body vibration training at home.
The patients were standing in an upright position receiving vertical vibration of
frequencies between 20-25 Hz. This vibration exercise evokes muscle contractions via stretch
reflexes improving muscular activity. The training schedule consisted of three 3-minute
sessions twice a day 5 days per week for 3 months.
Every 4 weeks the patients were seen for assessment of muscle function to evaluate the
effects of this new intervention.
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Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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