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Study of Total Energy Expenditure in Infants and Children With Moderate to Severe Cystic Fibrosis

Cystic Fibrosis Clinical Trial

Official title:
Study of Total Energy Expenditure in Infants and Children With Moderate to Severe Cystic Fibrosis

Clinical Trial Summary

OBJECTIVES: I. Compare the resting energy expenditure using respiratory calorimetry in infants and children with moderate to severe cystic fibrosis versus age matched healthy controls.

II. Determine the total energy expenditure and energy spent on physical activity using the doubly labeled water method in these patient populations.

Clinical Trial Description

PROTOCOL OUTLINE: Patients and healthy controls receive an oral dose of doubly labeled water following initial urine collection on day 1. Patients undergo additional urine collection at 4-6 hours following doubly labeled water consumption and then daily for 7 days.

Additionally, at the beginning of the study, patients and healthy controls undergo respiratory calorimetry over approximately 45 minutes at rest, starting approximately 2-3 hours after the last meal consumption and last use of aerosol bronchodilators (if required). ;

Study Design

Observational Model: Natural History

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00006273
Study type Observational
Source National Center for Research Resources (NCRR)
Contact
Status Active, not recruiting
Phase N/A
Start date June 1996
View Details
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