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Cutis Laxa clinical trials

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NCT ID: NCT06333067 Recruiting - Lax Skin Clinical Trials

Treatment to Lift Facial Lax Skin and Improve Facial Wrinkles Using Precise and Lift Applicators

Start date: October 11, 2023
Phase: N/A
Study type: Interventional

Open-label, non-randomized single-arm prospective, multi-center, self-controlled clinical study with masked evaluation.

NCT ID: NCT06330350 Recruiting - Quality of Life Clinical Trials

Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling

Start date: January 1, 2024
Phase:
Study type: Observational

The goal of this observational study is to understand the perspectives and needs of patients with genodermatoses and their partners who wish to have children, regarding their decision-making process and their consideration of reproductive options. Additionally, the investigators aim to investigate the level of knowledge and perspectives of healthcare professionals (such as clinical geneticists, dermatologists and other clinicians involved), and want to explore to what extent patients and their partners are well informed about these reproductive options. To achieve this, the investigators will conduct individual semi-structured qualitative interviews with participants affected by genodermatoses (and their partners) and with healthcare professionals.

NCT ID: NCT06243744 Recruiting - Skin Laxity Clinical Trials

Histological Evaluation of Human Skin Bx to Assess the Effects of APR Tx as an Adjunct Procedure in Facelift Surgery

Start date: November 30, 2023
Phase: N/A
Study type: Interventional

The goal of this prospective, single-arm clinical study is to gather quantifiable data on Renuvion's impact on skin elasticity and hydration, indicators of skin quality and estimate the biological skin age using DNA methylation in males and females between 18 and 75 years of age who plan to receive a lower facelift surgery. The main purpose is to quantify the effect of the Renuvion device on skin elasticity (collagen density, elastin, fibrillin-1), hydration (aquaporin-3, acidic glycosaminoglycans, HA), and DNA methylation to estimate the biological age of the skin. Participants will receive a lower facelift surgery per the Investigator's standard clinical practice and treatment with the Renuvion APR System.

NCT ID: NCT06231914 Recruiting - Laxity; Skin Clinical Trials

Efficacy and Safety of Fractional 1064-nm Picosecond Laser for Facial Skin Tightening

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn the efficacy and safety of fractional 1064-nm picosecond laser for facial skin tightening. The main questions it aims to answer are: - Efficacy of fractional 1064-nm picosecond laser for facial skin efficacy including the changes in wrinkle, nasolabial fold, skin laxity, and skin elasticity - The changes in texture and pore volume using Antera - The changes in bioengineering assessment: melanin index, erythema index, sebum level - Adverse events Participants will be treated with 3 sessions of fractional 1064-nm picosecond laser (full face 4 passes, vector lines 4 passes), spaced 4 weeks apart. Follow-up visits 1, 3, and 6 months after the last treatments.

NCT ID: NCT06157567 Recruiting - Wrinkle Clinical Trials

Clinical Feasibility Study to Evaluate the Safety and Performance of the Profound Matrix System

Start date: May 24, 2022
Phase: N/A
Study type: Interventional

This is a non-randomized, multi-center, open-label clinical trial evaluating clinical feasibility treatments with the Profound Matrix system.

NCT ID: NCT05986799 Recruiting - Skin Laxity Clinical Trials

The Efficacy of Amway Herbal Drink to Improve Skin Anti-aging

Start date: August 13, 2023
Phase: N/A
Study type: Interventional

This goal of this two arms, randomized, double-blind controlled trial is to study whether Amway herbal drink could improve skin anti-aging in the middle-aged people of 30-60 years old. The main questions it aims to answer are: 1. whether skin elasticity will be improved measured by Cutometer 2. whether skin wrinkles/roughness/pores will be improved measured by Antera 3D 30 eligible Participants will be enrolled in one center and randomly assigned to two study groups (Amway herbal drink group and placebo drink group). Up to four study visits will be made by the subject over a 3-month period intervention and all clinical data will be captured and recorded into CTMS (Clinical Trial Management System) for data analysis and reporting. Researchers will compare Amway herbal drink group and placebo drink group to see if consumption of Amway herbal drink could significantly improve skin anti-aging at the end of the study.

NCT ID: NCT05940038 Recruiting - Skin Laxity Clinical Trials

Retrospective Study of the Safety and Efficacy of PLLA for Skin Flaccidity in Labia Majora and/or Pubis Region

Start date: August 23, 2023
Phase:
Study type: Observational

Phase IV, retrospective, single-center, clinical trial, chart review to evaluate the safety and efficacy of poly-L-l-lactic acid [PLLA-SCA, Sculptra®] in women who underwent at least one treatment for skin flaccidity of the labia majora and/or pubis region for safety evaluation and three treatment sessions for efficacy evaluation.

NCT ID: NCT05773924 Recruiting - Wrinkle Clinical Trials

Evaluation of Efficacy and Safety of the triLift™ System

LUM-triLift
Start date: February 10, 2023
Phase: N/A
Study type: Interventional

Single center, single-arm, prospective, open Label with Before & After Study Design.

NCT ID: NCT05750901 Recruiting - Skin Laxity Clinical Trials

Evaluation of Fractional Ablative Laser Treatment for Skin Conditions

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

Evaluate the safety and efficacy of the fractional ablative laser for treatment of skin laxity and tightening

NCT ID: NCT05480098 Recruiting - Ptosis, Eyelid Clinical Trials

Brimonidine for Intraoperative Hemostasis

Start date: May 26, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to observe and report the effects of topical ophthalmic brimonidine in oculofacial plastic surgery.