Curcumin Use for Gynecological Conditions Clinical Trial
Official title:
Curcumin Supplementation for Gynecological Diseases Including Pelvic Inflammatory Disease Endometritis, Endometriosis: A Pilot Study
To use curcumin supplementation as an additive treatment to induce clinical, biochemical
response and remission in patients with suspected Pelvic inflammatory disease, Tubo ovarian
abcess, Endometritis, wound infection.
Hypothesis: An addition of oral curcumin to highly suspected PID/Endometritis/Wound infection
patients may augment clinical and biochemical response and accelerates the improvements of
the sign symptoms and reported outcomes of those diseases.
Pelvic inflammatory disease (PID), Endometritis, Wound infection are infections of the female
reproductive system. Although PID is a well known pathophysiology the diagnosis method I not
well established and its true magnitude is unknown. Many women report that they have been
treated for PID when they did not suffer from it and vice versa. Hence the main way to
diagnose remains clinical and currently there is no well-established biochemical marker. In
endometritis and wound infection the cause may be known but the pathogens involved in the
disease formation vary as for this broad spectrum antibiotic is needed.
Aims: To use curcumin supplementation as an additive treatment to induce clinical,
biochemical response and remission in patients with suspected PID, Tubo ovarian abcess,
Endometritis, wound infection.
Hypothesis: An addition of oral curcumin to highly suspected PID/Endometritis/Wound infection
patients may augment clinical and biochemical response and accelerates the improvements of
the sign symptoms and reported outcomes of those diseases.
Rational: Curcumin treatment has been shown to safe and efficient in inflammatory states such
as in mild-moderate Ulcerative colitis (UC), obesity, and type II diabetes mellitus when used
as an add-on to conventional treatment.
In the gynecology and especially in the PID/Tubo ovarian abcess diseases the use of Curcumin
as a supplement has never been studied.
In the future it is necessary to study the use of curcumin in different gynecological
diseases (e.g Endometriosis/Premenstrual syndrome (PMS) and also in gynecology oncology) in
which inflammatory and immune response are involve in the disease.
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