Clinical Trials Logo
  1. Home
  2. CTEPH
  3. NCT06105242

Biological Sex and CTEPH-related RV Dysfunction and Recovery (BIOSPHeRe)

CTEPH Clinical Trial

Official title:
Biological Sex and Sex Hormones Moderate Right Ventricular (RV) Dysfunction and Recovery in Chronic Thromboembolic Pulmonary Hypertension

Clinical Trial Summary

1. To identify biological sex differences in baseline RV function in CTEPH 2. To identify biological sex differences in recovery of RV function after PTE surgery in CTEPH 3. To determine if sex hormone levels relate to RV function at CTEPH diagnosis and during recovery after PTE.

Clinical Trial Description

Aims 1 and 2 together comprise a retrospective cohort study. We will identify historical subjects with newly diagnosed CTEPH using a clinical database. We will perform TTE strain analysis (RVGLS) to compare RV function between the biologic sexes at diagnosis and after surgical correction of CTEPH (to assess recovery). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06105242
Study type Observational [Patient Registry]
Source Intermountain Health Care, Inc.
Contact
Status Recruiting
Phase
Start date May 30, 2022
Completion date December 31, 2026
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT05140525 - Effects of Combination Medical Therapy Followed by BPA on Right Ventricular-PA Coupling and Hemodynamics in CTEPH Phase 3
Completed NCT03083093 - CTEPH Identification an Standard Computerised Tomography Pulmonary Angiography in Pulmonary Embolism Patients
Completed NCT04730037 - Clinical Trial to Investigate Safety and Efficacy of Edoxaban in Patients With CTEPH (KABUKI) Phase 3
Completed NCT03245268 - International BPA Registry
Recruiting NCT02660463 - Prospective Registry to Evaluate the Effective Incidence of Chronic Thromboembolic Pulmonary Hypertension in Germany N/A
Completed NCT01393327 - Feasibility and Influence of Exercise Therapy on Oxygen Uptake and Right Heart Function in CTEPH Patients After PEA N/A
Recruiting NCT01672203 - Chronic Thromboembolic Pulmonary Hypertension (CTEPH) Incidence in Patients With Central Versus Peripheral Embolism N/A
Completed NCT03953560 - Symptom-related Screening for Early Detection of CTEPH. N/A
Completed NCT02656238 - New International CTEPH Database
Recruiting NCT05480137 - OCT Evaluates the Effects of CTEPH Treated by Scoring Balloon N/A
Terminated NCT03273257 - Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study) Phase 2
Recruiting NCT05629052 - TrEatment Approach in the Multimodal Era Registry
Completed NCT04207593 - The Effect of Oxygen Therapy on 6MWD in PAH and CTEPH Patients With Hypoxemia Phase 2