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Biological Sex and CTEPH-related RV Dysfunction and Recovery (BIOSPHeRe)

CTEPH Clinical Trial

Official title:
Biological Sex and Sex Hormones Moderate Right Ventricular (RV) Dysfunction and Recovery in Chronic Thromboembolic Pulmonary Hypertension

Clinical Trial Summary

1. To identify biological sex differences in baseline RV function in CTEPH 2. To identify biological sex differences in recovery of RV function after PTE surgery in CTEPH 3. To determine if sex hormone levels relate to RV function at CTEPH diagnosis and during recovery after PTE.

Clinical Trial Description

Aims 1 and 2 together comprise a retrospective cohort study. We will identify historical subjects with newly diagnosed CTEPH using a clinical database. We will perform TTE strain analysis (RVGLS) to compare RV function between the biologic sexes at diagnosis and after surgical correction of CTEPH (to assess recovery). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06105242
Study type Observational [Patient Registry]
Source Intermountain Health Care, Inc.
Contact
Status Recruiting
Phase
Start date May 30, 2022
Completion date December 31, 2026
View Details
See also
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