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Cryptorchidism clinical trials

View clinical trials related to Cryptorchidism.

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NCT ID: NCT06187844 Not yet recruiting - Undescended Testis Clinical Trials

Value of Inguinal Exploration for Impalpable Testes

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

- To determine the percentage of children with impalpable testis who benefit from inguinal exploration after laparoscopic identification of cord structures entering the inguinal canal. - To determine the factors predicting the presence of inguinal testis in the previously mentioned children.

NCT ID: NCT05845515 Active, not recruiting - Clinical trials for We Conducted This Prospective Randomized Comparative Study to Compare Between Outcome of Laparoscopic and Open Orchiopexy of High Inguina

Laparoscopic Versus Open Orchiopexy in High Inguinal Undescended Testis, Prospective Randomized Clinical Trial

Start date: January 1, 2018
Phase: Phase 4
Study type: Interventional

We conducted this prospective randomized comparative study to compare between outcome of laparoscopic and open orchiopexy of high inguinal. All children presented to us with high inguinal undescended testis diagnosed by history, clinical examination and inguino-scrotal ultrasound were included in this study. We exclude children with previous history of inguinal surgery or unfit for anesthesia. 150 patients with inclusion criteria were randomized (using block randomization method by Stata, version 13.1, StataCorp, for Microsoft Windows R) into two groups: Group A: 75 cases who were operated with laparoscopic orchiopexy. Group B: 75 cases who were operated with open orchiopexy. All of the patients were subjected to the following: Complete history taking, and Clinical examination: High inguinal undescended testis, is testicle felt at upper half of inguinal canal and can't manipulated to the scrotum Pre-operative routine Laboratory investigation and Pre-operative imaging: Inguino-scrotal & colored Doppler ultrasound, were done for all patients. Patients were kept on fasting for 6 hours for solid food 2 hours for fluids before surgery. Informed written consent from all parents was obtained. All patients in our study underwent general anesthesia.

NCT ID: NCT05558748 Recruiting - Analgesia Clinical Trials

"Comparison of USG-Guided Caudal Versus Ilioinguinal/Iliohypogastric Nerve Block for Pediatric Inguinal Surgeries"

CAUCIN
Start date: December 6, 2022
Phase: N/A
Study type: Interventional

This study is designed to compare the analgesic effectiveness of caudal analgesia to ilioinguinal regional analgesia techniques in children undergoing inguinal surgeries. Both techniques will be done under ultrasound gaudiness, using the same local anesthesia. 128 patients will be included in this study, 64 for each technique. This study aims to know the best regional analgesia technique in children undergoing inguinal surgeries, reduction in rescue analgesia postoperatively, postoperative length of stay, and early resumption of postoperative activity. The patients will be followed up 30 minutes after the end of anesthesia in PACU, postoperatively in Ward at 2 Hours, 3 hours, 6 hours from the end of anesthesia, and or at the time of discharge from the ward & on days 2 and 7. Patient privacy and safety will be respected at all times. An interim analysis will be done after recruiting 25% of cases (16 cases) in both arms. Once the sample size is reached, the data will be sent for statistical analysis with coded patient identity. Based on study findings, the practice will be optimized with the aim of improvement in pain relief, reduction in opioid requirements, and enhanced recovery after surgery (ERAS), reducing the bed occupancy time in the hospital.

NCT ID: NCT05097820 Recruiting - Testicular Cancer Clinical Trials

Prospective Observational Study on SEBBIN Silicone Gel-filled Testicular Implants

Start date: February 5, 2021
Phase:
Study type: Observational [Patient Registry]

To analyze the short and long term postoperative clinical outcome and patient satisfaction of silicone gel-filled testicular implants.

NCT ID: NCT04841018 Completed - Clinical trials for Patients With Cryptorchism Who Are Planning to Undergo Orchiopexy

Does Low Dose of Dexamethasone Enhance Analgesic Quality of Caudal Analgesia in Children Undergoing Orchiopexy?

Start date: March 24, 2021
Phase: N/A
Study type: Interventional

Caudal block is one of the most effective modalities to reduce pain both during and after the surgery involving areas under the umbilicus. According to previous research, 0.5mg/kg-1.5mg/kg dexamethasone is known to enhance the analgesic quality of caudal block in children. Despite the fact that this high dose of dexamethasone is used to treat airway edema in actual practice and no adverse side effect related to dosage has been reported, it is 3 to 15 times higher than the daily antiemetic dose of dexamethasone that is used in standard care of anesthesia. Therefore, our study aims to assess the effect of the more practical, antiemetic dose of dexamethasone (0.15mg/kg) as an adjuvant to enhance the quality of caudal block through a non-inferiority trial.

NCT ID: NCT04826484 Terminated - Urologic Diseases Clinical Trials

Opioid Reduction Initiative During Outpatient Pediatric Urologic Procedures Using Exparel

Baby ORIOLES
Start date: October 1, 2021
Phase: Phase 3
Study type: Interventional

This study aims to evaluate the utility of long-acting liposomal bupivacaine (Exparel®) in improving pain scores and reducing narcotic pain requirements in pediatric patients following minor urologic procedures.

NCT ID: NCT04821167 Completed - Testes Undescend Clinical Trials

Safety and Efficiency of Laparoscopic Management of Intra-canalicular (Emergent) Testis

LapUDT
Start date: January 1, 2019
Phase: N/A
Study type: Interventional

Undescended testes (UDTs) are a relatively common finding in pediatrics with prevalence about 1-2% in newborns. Upon discovering a non-intrascrotal testis, it is important to determine whether the testis is palpable or non-palpable (1). A canalicular or 'emergent' testis may be impalpable initially and may be appear when it is 'milked' out of the inguinal canal (where it is concealed from detection) indicating that 15 to 40% of cryptorchidism are viable peeping/canalicular testis. The laparoscopic approach for treating canalicular undescended testes offers many advantages over open inguinal orchiopexy. The laparoscopic technique maintains the integrity of the inguinal canal anatomy and eliminating the need to divide the epigastric vessels during dissection. The ability to dissect the testicular vessels at a higher extent would increase the vessel length available to lower the testis without strain. - This is a prospective study will be conducted at Department of Pediatric Surgery, MCH hospital, Bisha, Saudia Arabia and Pediatric surgery Department , Al-Azhar University hospitals, Cairo, Egypt, from January 2019 to October 2020 to evaluate the safety and efficiency of laparoscopic orchiopexy of intracanalicular testis. - Patients' age and laterality will be reported. Evaluation will be done for the operative difficulties, intraoperative complications, operative time and early postoperative complications. Testicular site, size and vascularity will be evaluated by ultrasonography at 6th month post operatively. Also, cosmetic results will be evaluated by obtaining the parent's questioners at post-operative OPD clinic visits. - Laparoscopic orchiopexy for management of inguinal canalicular undescended testes is a safe, effective, and less invasive, without disturbance of inguinal canal anatomy, with better cosmetic results.

NCT ID: NCT04696874 Completed - Epididymal Cyst Clinical Trials

Spectrum of Epididymis and Vas Deferens Anomalies Among Children With Cryptorchidism

Start date: September 1, 2017
Phase:
Study type: Observational [Patient Registry]

: Data was collected retrospectively from six centers providing care for patients with undescended testicles from September 2017 to February 2019. All patients whose congenital anomalies of the epididymis or vas deferens were discovered incidentally during operative intervention for cryptorchidism and where photographs of the anomalies were taken were included.

NCT ID: NCT04528381 Not yet recruiting - Undescended Testes Clinical Trials

Role of Laparoscopy in Management of Non-palpable Undescended Testis : Assuit University Experience

Start date: August 2020
Phase: N/A
Study type: Interventional

1. To evaluate the role of laparoscopy in diagnosis & treatment of Non- palpable undescended testis 2. To compare between different laparoscopic techniques 3. To introduce new laparoscopic technique in Assuit university " shehata technique "

NCT ID: NCT04342026 Recruiting - Cryptorchidism Clinical Trials

Role of the Environment and Endocrine Disruptors in Child Cryptorchidism

CRYPTENV
Start date: April 16, 2020
Phase:
Study type: Observational

Cryptorchidism is the most frequent congenital defect of the male newborn. It requires surgery in childhood, increases the risk of fertility disorders and cancer. As a major public health objective, it's the subject of numerous recommendations. Its frequency is increasing in some countries faster than a single genetic cause could not explain it. It may occurs in a geographic cluster. The cause of cryptorchidism involves genetic, hormonal and environmental factors. Animal studies suggest that endocrine disruptors interfere with fetal testicular migration. The aim of the study is to find out if some environmental exposition may be associated with cryptorchidism.