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Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients — ATOMIC  

Critical Illness Clinical Trial

Official title:
Parenteral Magnesium Prophylaxis for the Prevention of New-Onset Atrial Fibrillation in Critically Ill Patients - a Pilot Feasibility Study

Clinical Trial Summary

A double-blind, multi-centre, randomized, placebo-controlled, feasibility pilot trial in the prevention of new onset atrial fibrillation of critically ill patients admitted to an ICU.

Clinical Trial Description

Most studies of new onset atrial fibrillation (NOAF) in critical illness focus on treatment of this arrhythmia but this innovative study will focus on prevention. Parenteral Mg is a low cost and readily available treatment that may be beneficial for reducing the incidence of NOAF in critically ill patients, with the potential to improve patient centred outcomes and provide a cost effective prophylaxis. The main outcome of this study is to determine if it is feasible to conduct a randomized controlled trial comparing parenteral magnesium sulfate with placebo for the prophylaxis of new onset atrial fibrillation in critically ill patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05829317
Study type Interventional
Source Queen's University
Contact Miranda Hunt
Phone 613 549 6666
Email miranda.hunt@kingstonhsc.ca
Status Recruiting
Phase Phase 4
Start date August 20, 2023
Completion date July 2025
View Details
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