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Clinical Trial Summary

This is a Phase 1, single-arm, single-center, open-label study to evaluate the safety and effectiveness of NKG2D-based CAR-T cells infusion in the treatment of advanced NKG2DL+ solid tumors.


Clinical Trial Description

This is an open-label, dose escalation/expansion study to assess the safety, tolerability, and efficacy of KD-025 cell infusion in patients with advanced NKG2DL+ solid tumors. In this study, the enrollment of the patients must meet the inclusion and exclusion criteria. All subjects will be undergo screening, pre-treatment (cell product preparation, lymphodepleting chemotherapy), treatment and follow up. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05382377
Study type Interventional
Source The Affiliated Hospital of the Chinese Academy of Military Medical Sciences
Contact Jianming Xu, M.D
Phone 13910866712
Email jianmingxu2014@163.com
Status Recruiting
Phase Early Phase 1
Start date May 17, 2022
Completion date May 17, 2026

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