Clinical Trials Logo
  1. Home
  2. Craniosynostosis
  3. NCT03231085

Comparison of the Rate of Preoperative Haemoglobin After Administration of Epoetin Alpha Associated With an Oral Medical Supplementation Versus Intravenous Before Surgery of Craniosynostosis at the Child — IRON KID  

Craniosynostosis Clinical Trial

Official title:
Comparison of the Rate of Preoperative Haemoglobin After Administration of Epoetin Alpha Associated With an Oral Medical Supplementation Versus Intravenous Before Surgery of Craniosynostosis at the Child

Clinical Trial Summary

Oral iron is commonly used in conjunction with EPO preoperatively for hemorrhagic surgeries in children and especially in the surgery of craniosynostosis. The bioavailability of oral iron is low and compliance with treatment is inconsistent. The aim of this study is to evaluate whether the use of ferric carboxymaltose by injection, which has a much better bioavailability, would make it possible to increase the preoperative hemoglobin level more effectively and thus reduce the risk of perioperative blood transfusion .

Clinical Trial Description

Prospective study, randomized in two parallel groups (martial treatment versus venous injection) and stratified by center (Montpellier, Nice, Angers). The number of subjects required is 100 patients, or 50 per group. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03231085
Study type Interventional
Source University Hospital, Montpellier
Contact Philippe PIRAT, MD
Phone 0467338256
Email p-pirat@chu-montpellier.fr
Status Recruiting
Phase N/A
Start date October 31, 2017
Completion date December 2024
View Details
See also
  Status Clinical Trial Phase
Withdrawn NCT00769847 - Endoscopic Treatment for Isolated, Single Suture Craniosynostosis N/A
Completed NCT00077831 - Child and Infant Learning Project N/A
Active, not recruiting NCT02229968 - Efficacy of Amicar for Children Having Craniofacial Surgery Phase 2
Completed NCT02287805 - Qualitative and Quantitative Study Which Aims to Determine the Specifics of the Announcement for the Diagnosis of Patients With Craniosynostosis and Their Parents to Better Support Them in Their Care N/A
Enrolling by invitation NCT05911139 - Influence of General Anesthesia on the Dynamic Changes in Brain Damage Markers During and After Craniosynostosis Operations in Infancy
Completed NCT00912119 - Amicar Pharmacokinetics of Children Having Craniofacial Surgery Phase 1
Completed NCT00106977 - Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)
Withdrawn NCT02561728 - Hanger Helmet Study N/A
Terminated NCT00722436 - Tranexamic Acid for Craniofacial Surgery Phase 4
Completed NCT00367796 - Genetic Analysis of Craniosynostosis, Philadelphia Type N/A
Completed NCT01898650 - MRI for Non-invasive Evaluation of Brain Stress N/A
Active, not recruiting NCT03025763 - Network Of Clinical Research Studies On Craniosynostosis, Skull Malformations With Premature Fusion Of Skull Bones
Completed NCT02188576 - The Efficacy and Population Pharmacokinetics of Tranexamic Acid for Craniosynostosis Surgery Phase 4
Completed NCT00773643 - Osteogenic Profiling of Tissue From Children With Craniosynostosis N/A
Enrolling by invitation NCT04704284 - Comparing MRI to CT on Pediatric Craniosynostosis. N/A