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Comparison of the Rate of Preoperative Haemoglobin After Administration of Epoetin Alpha Associated With an Oral Medical Supplementation Versus Intravenous Before Surgery of Craniosynostosis at the Child — IRON KID  

Craniosynostosis Clinical Trial

Official title:
Comparison of the Rate of Preoperative Haemoglobin After Administration of Epoetin Alpha Associated With an Oral Medical Supplementation Versus Intravenous Before Surgery of Craniosynostosis at the Child

Clinical Trial Summary

Oral iron is commonly used in conjunction with EPO preoperatively for hemorrhagic surgeries in children and especially in the surgery of craniosynostosis. The bioavailability of oral iron is low and compliance with treatment is inconsistent. The aim of this study is to evaluate whether the use of ferric carboxymaltose by injection, which has a much better bioavailability, would make it possible to increase the preoperative hemoglobin level more effectively and thus reduce the risk of perioperative blood transfusion .

Clinical Trial Description

Prospective study, randomized in two parallel groups (martial treatment versus venous injection) and stratified by center (Montpellier, Nice, Angers). The number of subjects required is 100 patients, or 50 per group. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03231085
Study type Interventional
Source University Hospital, Montpellier
Contact Philippe PIRAT, MD
Phone 0467338256
Email p-pirat@chu-montpellier.fr
Status Recruiting
Phase N/A
Start date October 31, 2017
Completion date June 2024
View Details
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