Craniopharyngioma Clinical Trial
Official title:
Tumor Classification and Its Application in Surgical Treatment of Craniopharyngioma
With the preliminary anatomical and histological study, the membranous structures of the sellar region was considered to be closely related with the growth pattern of Craniopharyngiomas(CP). By combined considering of the tumor-membrane relationship, this project was trying to classify the CP through retrospectively summarizing the pre- and postoperative imaging (MRI and CT), the intrasurgical findings, and the endocrine data of 198 CPs with primary surgery in our hospital (since 1997 until now). As a result, a distinct and systematic CP classification was proposed. The possible originate site, surgical skills and postoperative treatment of all the subtype tumors were discussed and analyzed to provide a normalized surgical treatment for this kind of tumor. Then in the prospective cohort, the anticipated 100 CP patients will accept the normalized surgical treatment. And by the long term follow up, the postsurgical quantity of life (QOL) of patients was evaluated with aspect in cognition, circadian rhythm, endocrine, Water-Electrolyte and body weight, et al. By comparing with the long-term results of the retrospective cohort, the totally follow up data was statistically analyzed to assess the rationality of this standard treatment of CP.
n/a
Observational Model: Cohort, Time Perspective: Cross-Sectional
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05465174 -
Nivolumab and Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults
|
Phase 2 | |
Recruiting |
NCT05525273 -
Treatment of BRAF ( B-Rapidly Accelerated Fibrosarcoma) Mutated Papillary Craniopharyngioma
|
Phase 2 | |
Completed |
NCT02849743 -
Intranasal Oxytocin in Hypothalamic Obesity
|
Phase 2 | |
Completed |
NCT01272622 -
Prospective Study of Children and Adolescents With Craniopharyngioma
|
N/A | |
Recruiting |
NCT04158284 -
Multicenter Registry for Patients With Childhood.Onset Craniopharyngioma, Xanthogranuloma, Cysts of Rathke's Pouch, Meningioma, Pituitary Adenoma, Arachnoid Cysts
|
||
Completed |
NCT03194906 -
Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors
|
Phase 2 | |
Recruiting |
NCT06217848 -
The Effect of GLP-1 Agonist in Patients With Hypothalamic Obesity: Prospective, Pilot Study
|
Early Phase 1 | |
Completed |
NCT01881854 -
Sleep Wake and Melatonin Pattern in Craniopharyngioma
|
N/A | |
Active, not recruiting |
NCT00517959 -
SCRT Versus Conventional RT in Children and Young Adults With Low Grade and Benign Brain Tumors
|
Phase 3 | |
Not yet recruiting |
NCT06299891 -
Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity
|
Phase 2 | |
Completed |
NCT02842723 -
Management of Pediatric Craniopharyngioma by a Combination of Partial Surgical Resection, and Protontherapy (Craniopharyngioma)
|
Phase 2 | |
Recruiting |
NCT02792582 -
A Phase II Trial of Intensity-Modulated Proton Therapy for Incompletely Resected Craniopharyngioma and Observation for Craniopharyngioma After Radical Resection
|
Phase 2 | |
Completed |
NCT01484873 -
Weight Loss Study for Patients With Obesity Due to Craniopharyngioma or Other Brain Tumor
|
Phase 2 | |
Withdrawn |
NCT03708913 -
Neuromodulation for Hypothalamic Obesity
|
N/A | |
Completed |
NCT02162732 -
Molecular-Guided Therapy for Childhood Cancer
|
N/A | |
Recruiting |
NCT00840047 -
Methionine PET/CT Studies In Patients With Cancer
|
Phase 2 | |
Recruiting |
NCT04087902 -
Long-Term Longitudinal QoL in Patients Undergoing EEA
|
||
Recruiting |
NCT04648462 -
Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology
|
||
Completed |
NCT04937335 -
Craniopharyngioma With Tumoral Hemorrhage
|
||
Completed |
NCT03330080 -
Examination of Sleep and Family Functioning in Pediatric Craniopharyngioma Patients
|