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Cow Milk Allergy clinical trials

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NCT ID: NCT03236207 Completed - Cow Milk Allergy Clinical Trials

Hypoallergenicity Evaluation of a New Extensively Hydrolyzed Formula

Start date: July 6, 2017
Phase: N/A
Study type: Interventional

Infants/children with cow's milk allergy will take part in 2 double-blinded placebo-controlled food challenges (DBPCFC) of 2 extensively hydrolyzed formulas in random order. If both food challenges are passed, subjects will be asked to consume the Test formula in an at-home open challenge for 7 days.

NCT ID: NCT03223181 Recruiting - Cow Milk Allergy Clinical Trials

Assessment of Cow's Milk-related Symptom Scoring Awareness Tool in Young Turkish Children

Start date: June 8, 2015
Phase: N/A
Study type: Observational

In this study the investigators aimed to evaluate diagnostic accuracy the scoring tool used to determine cow's milk protein allergy, the cow's milk related symptom score, is based on the gastrointestinal, respiratory system and dermatological symptoms being together in young Turkish children.

NCT ID: NCT03004729 Completed - Cow Milk Allergy Clinical Trials

Symptoms Based Awareness Confirmation Study - CoMiSS Validation

MOSAIC
Start date: December 2016
Phase: N/A
Study type: Interventional

The Cow's Milk-related Symptom Score (CoMiSS) tool has been developed to define a score to recognize cow's milk related symptoms in infants and young children. Many infants and toddlers with symptoms that can be related to intake of cow's milk and cow's milk protein allergy (CMPA) are often not diagnosed due to the lack of specific markers. The goal of this trial is to validate the CoMiSS tool in infants suspected of CMPA and investigate if the CoMiSS tool could be an alternative to the open challenge test needed to confirm the diagnosis of Cow Milk Protein Allergy.

NCT ID: NCT02785679 Recruiting - Cow Milk Allergy Clinical Trials

The Influence of Early and Continuous Exposure of Infants to Cow's Milk Formula on the Prevention of Milk Allergy

Start date: March 20, 2018
Phase: N/A
Study type: Interventional

Cow's milk protein (CMP) allergy is one of the most common food allergies and potentially a fatal one. Early feeding with CMP has been considered in the past as a risk factor for development of CMP allergy in high risk infants. Although other studies argue with this assumption and suggest early exposure to CMP might be protective against atopic dermatitis and CMP allergy. A cohort study that first introduction of CMP after 15-30 days of age, raised the risk for CMP allergy.The aim of this study is to investigate if early and continuous exposure to CMF will decrease CMP allergy rate.

NCT ID: NCT02711163 Completed - Cow Milk Allergy Clinical Trials

Evaluation of the Hypoallergenicity of an Extensively Hydrolyzed Formula

ALYCE
Start date: April 2016
Phase: Phase 3
Study type: Interventional

The aim of this study is to assess the hypoallergenicity of a new thickened extensively hydrolyzed formula, in infants with confirmed cow's milk protein allergy assessed through a double blind placebo controlled food challenge, followed by a 3-month open feeding period.

NCT ID: NCT02351531 Completed - Cow Milk Allergy Clinical Trials

Cow Milk Allergy: Evaluation of the Efficacy of a New Thickened Extensively Hydrolyzed Formula in Infants With Confirmed Cow Milk Allergy

COMETE
Start date: November 2013
Phase: Phase 3
Study type: Interventional

The aim of the study is to assess the hypoallergenicity of a new thickened extensively hydrolyzed formula.

NCT ID: NCT02087930 Recruiting - Cow Milk Allergy Clinical Trials

Microbiota as Potential Target for Food Allergy

MATFA
Start date: March 2013
Phase:
Study type: Observational

Food allergy (FA) derives from a dysregulation of oral tolerance mechanisms. Studies suggest a crucial role for enteric microflora in oral tolerance development. An altered composition of intestinal microflora results in an unbalanced local and systemic immune response to food allergens. There are qualitative and quantitative differences in gut microbiota composition in children with food allergy. These findings support the concept that specific beneficial bacteria from human intestinal microflora, designated probiotics, could restore intestinal microflora homeostasis and prevent or treat FA.

NCT ID: NCT01940068 Completed - Cow Milk Allergy Clinical Trials

A Double-blind Randomized Controlled Trial of a Thickened Amino-acid-based Formula in Children Allergic to Cow's Milk and to Protein Hydrolysates

Start date: March 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the impact of a new Amino-acid based formula on allergic symptoms and growth of infants with cow's milk protein allergy and intolerant to extensively hydrolysed formulas;

NCT ID: NCT01637688 Active, not recruiting - Cow Milk Allergy Clinical Trials

Growth and Plasma Amino Acids in Infants With CMPA and Treated With a Newly Innovated Amino Acid Formula

CMPA
Start date: April 1, 2013
Phase:
Study type: Observational

The purpose of this study is to determine growth and protein status of infants with cow's milk protein allergy and treated with a newly innovated amino acid formula compared to those with a commercial amino acid formula.

NCT ID: NCT00874627 Completed - Cow Milk Allergy Clinical Trials

Sublingual Milk Immunotherapy in Children

Lactaide
Start date: September 2008
Phase: N/A
Study type: Interventional

Sublingual immunotherapy is developing in the treatment of aeroallergens allergy. The hypothesis is that such process may be applied to food allergy, more precisely to milk. A previous series of 8 patients indicates the likely effectiveness of this technique (Allergy, 2006).