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Cow Milk Allergy clinical trials

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NCT ID: NCT03874104 Completed - Cow Milk Allergy Clinical Trials

Synbiotic Extensively Hydrolysed Feed Study

Start date: August 22, 2018
Phase: N/A
Study type: Interventional

This study of the tolerance and acceptability of a extensively hydrolysed formula (eHF) containing pre- and probiotics will assess gastrointestinal (GI) tolerance, product intake and acceptability in 40 infants (aged <13 months) currently using or requiring an extensively hydrolysed formula for the dietary management of CMA. Patients already prescribed an eHF (or other appropriate feed for CMA) at time of recruitment will undertake a 3 day baseline period in which their current symptoms, compliance, GI tolerance and acceptability towards their current feed is assessed, before introducing the study product for a period of 4 weeks. Patients who are not on an eHF (or other appropriate feed for CMA) at baseline will forgo this 3 day baseline period and immediately introduce the study product for 4 weeks.

NCT ID: NCT03661736 Completed - Cow Milk Allergy Clinical Trials

Growth of Infants With Cow's Milk Allergy Fed an Amino Acid-based Formula Containing Two Human Milk Oligosaccharides

PLATYPUS
Start date: April 12, 2018
Phase:
Study type: Observational

The main aim of this study is to provide longitudinal growth data in infants with moderate-to-severe cow's milk allergy fed an amino acid-based formula with two added human milk oligosaccharides.

NCT ID: NCT03557671 Completed - Cow Milk Allergy Clinical Trials

Evaluation of the Hypoallergenicity of a New Formula Based on Hydrolyzed Rice Proteins

Start date: August 23, 2018
Phase: N/A
Study type: Interventional

The aim of this study is to show the hypoallergenicity of a new thickened rice based formula (TRHF) through a double blind placebo controlled food challenge (DBPCFC), as recommended by the American Academy of Pediatrics, in subjects with IgE-mediated CMA and in subjects with non-IgE-mediated CMA.

NCT ID: NCT03236207 Completed - Cow Milk Allergy Clinical Trials

Hypoallergenicity Evaluation of a New Extensively Hydrolyzed Formula

Start date: July 6, 2017
Phase: N/A
Study type: Interventional

Infants/children with cow's milk allergy will take part in 2 double-blinded placebo-controlled food challenges (DBPCFC) of 2 extensively hydrolyzed formulas in random order. If both food challenges are passed, subjects will be asked to consume the Test formula in an at-home open challenge for 7 days.

NCT ID: NCT03004729 Completed - Cow Milk Allergy Clinical Trials

Symptoms Based Awareness Confirmation Study - CoMiSS Validation

MOSAIC
Start date: December 2016
Phase: N/A
Study type: Interventional

The Cow's Milk-related Symptom Score (CoMiSS) tool has been developed to define a score to recognize cow's milk related symptoms in infants and young children. Many infants and toddlers with symptoms that can be related to intake of cow's milk and cow's milk protein allergy (CMPA) are often not diagnosed due to the lack of specific markers. The goal of this trial is to validate the CoMiSS tool in infants suspected of CMPA and investigate if the CoMiSS tool could be an alternative to the open challenge test needed to confirm the diagnosis of Cow Milk Protein Allergy.

NCT ID: NCT02711163 Completed - Cow Milk Allergy Clinical Trials

Evaluation of the Hypoallergenicity of an Extensively Hydrolyzed Formula

ALYCE
Start date: April 2016
Phase: Phase 3
Study type: Interventional

The aim of this study is to assess the hypoallergenicity of a new thickened extensively hydrolyzed formula, in infants with confirmed cow's milk protein allergy assessed through a double blind placebo controlled food challenge, followed by a 3-month open feeding period.

NCT ID: NCT02351531 Completed - Cow Milk Allergy Clinical Trials

Cow Milk Allergy: Evaluation of the Efficacy of a New Thickened Extensively Hydrolyzed Formula in Infants With Confirmed Cow Milk Allergy

COMETE
Start date: November 2013
Phase: Phase 3
Study type: Interventional

The aim of the study is to assess the hypoallergenicity of a new thickened extensively hydrolyzed formula.

NCT ID: NCT01940068 Completed - Cow Milk Allergy Clinical Trials

A Double-blind Randomized Controlled Trial of a Thickened Amino-acid-based Formula in Children Allergic to Cow's Milk and to Protein Hydrolysates

Start date: March 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the impact of a new Amino-acid based formula on allergic symptoms and growth of infants with cow's milk protein allergy and intolerant to extensively hydrolysed formulas;

NCT ID: NCT00874627 Completed - Cow Milk Allergy Clinical Trials

Sublingual Milk Immunotherapy in Children

Lactaide
Start date: September 2008
Phase: N/A
Study type: Interventional

Sublingual immunotherapy is developing in the treatment of aeroallergens allergy. The hypothesis is that such process may be applied to food allergy, more precisely to milk. A previous series of 8 patients indicates the likely effectiveness of this technique (Allergy, 2006).

NCT ID: NCT00664768 Completed - Cow Milk Allergy Clinical Trials

A Growth and Hypoallergenicity Study of a New Formula for Infants With Cow Milk Allergy

CMA
Start date: March 2008
Phase: N/A
Study type: Interventional

This study involves the use of 2 different Neocate formulas: a control formula called Neocate Infant and a test Neocate formula. These kinds of formulas are for use in children from birth to 8 months of age with Cow Milk Allergy (CMA), other food allergies, and other gastrointestinal disorders. The purpose of this study is to compare the control and test Neocate formulas for safety, tolerability, and effectiveness (in promoting growth) when used in subjects with CMA. This study will also look at the test Neocate formula to see if it is hypoallergenic when used in subjects with CMA.