Prevalence of ENT Diseseas

Long COVID Clinical Trial

— PrENT  

Official title:

Prevalence Study of ENT-related Diseases in Conscripts at the Military Induction Board

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06105346
• Other study ID #: PrENT v1
• Status: Not yet recruiting
• Start date: December 1, 2023
• Est. completion date: March 31, 2026

Study information

• Verified date: October 2023
• Source: Medical University of Graz
• Contact: Emanuel Maitz, MD
• Phone: 00436604756105
• Email: emanuel.maitz[@]medunigraz.at
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

The aim of the present study will be to evaluate in conscripts at the military induction board the prevalence of rhinosinusitis, the prevalence of HPV vaccinations, the prevalence of hearing impairments and the prevalence of long-COVID symptoms and further, to evaluate different factors that influence on the one hand the prevalence (urban-bred, non-urban-bred) and on the other hand symptoms (ENT-surgeries in medical history). Further, we want to evaluate if there is a correlation between subjective symptoms and apparated-based diagnostic investigations.

Therefore, questionnaires and data of medical examinations, aquired routinely at the military induction board, will be analysed.

Description:

Rhinosinusitis is a very common complaint at ENT departments, whereby symptoms of the underlying disease are varying. Therefore, there is growing interest in prevalence of rhinosinusitis including differences in prevalence's depending on where the patient grew up. Further, there is growing interest in answering the question if different factors, including ENT-surgeries in medical history have an impact on symptoms of rhinosinusitis.

Within the past few years there is growing interest in carring out as many HPV-vaccinations as possible in order to reduce the prevalence of HPV-associated cancers.

Further, in adolescents there is a growing number of hearing impairments, including hearing loss and/or sounds in the ears.

Next, since the beginning of the COVID pandemic there are very common complaints in adult and pediatric patients about persistent medical problems for weeks or months after an acute SARS-CoV-2-infection and cannot be explained by another diagnosis, called long- Covid disease.

The military induction board of conscripts enables access to data from a cross-section of the population, with common characteristics of gender and age.

In the present study we want therefore to evaluate in conscripts at the military induction board the prevalence of rhinosinusitis, the prevalence of HPV vaccinations, the prevalence of hearing impairments and the prevalence of long-COVID symptoms and further, to evaluate different factors that influence on the one hand the prevalence (urban-bred, non-urban-bred) and on the other hand symptoms (ENT-surgeries in medical history). Further, we want to evaluate if there is a correlation between subjective symptoms and apparated-based diagnostic investigations.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 10000
• Est. completion date: March 31, 2026
• Est. primary completion date: December 1, 2025
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 17 Years to 19 Years

Eligibility

Inclusion Criteria:

• participation of the military induction board of conscripts

• consent for participation obtained by the conscripts

• completed questionnaire (with at least 50% completeness of each subcategory)

• participation of medical examination

Exclusion Criteria:

• no consent for participation in the study by the conscripts

• incomplete questionnaire (with less than 50% completeness of each subcategory)

• no participation of medical examination.

Related Conditions & MeSH terms

• ENT Disease
• ENT Surgery
• HPV Infection
• HPV Vaccine
• Long COVID
• Otorhinolaryngologic Diseases
• Papillomavirus Infections
• Rhinosinusitis
• Rhinosinusitis Chronic
• Sinusitis

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Medical University of Graz

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Prevalence of rhinosinusitis	To assess whether there is a difference in prevalence of rhinosinusitis in urban-bred conscripts compared to non-urban-bred conscripts.	Through data collection, an average of 1 week
Primary	Prevalence of human papilloma virus vaccination	To assess whether there is a difference in prevalence of human papilloma virus vaccinations in urban-bred conscripts compared to non-urban-bred conscripts.	Through data collection, an average of 1 week
Primary	Prevalence of hearing impairment	To assess whether there is a difference in prevalence of hearing impairment in urban-bred conscripts compared to non-urban-bred conscripts.	Through data collection, an average of 1 week
Primary	Prevalence of long-COVID disease	To assess whether there is a difference in prevalence of long-COVID disease in vaccinated conscripts compared to no-vaccinated conscripts.	Through data collection, an average of 1 week
Secondary	Prevalence of rhinosinusitis	To assess prevalence of rhinosinusitis in conscripts at the military induction board	Through data collection, an average of 1 week
Secondary	Prevalence of rhinosinusitis	To assess the different symptoms of rhinosinusitis in conscripts at the military induction board	Through data collection, an average of 1 week
Secondary	Prevalence of rhinosinusitis	To assess the prevalence of rhinosinusitis in conscripts with previous ENT-surgeries	Through data collection, an average of 1 week
Secondary	Prevalence of rhinosinusitis	To assess differences in symptoms in rhinosinusitis in conscripts with previous ENT-surgeries	Through data collection, an average of 1 week
Secondary	Prevalence of rhinosinusitis	To assess the combined prevalence of rhinosinusitis and chronic pulmonary diseases in conscripts	Through data collection, an average of 1 week
Secondary	Prevalence of rhinosinusitis	To assess the difference in prevalence of subjective symptoms of rhinosinusitis compared to objective (apparatus based and laboratory based) symptoms of rhinosinusitis	Through data collection, an average of 1 week
Secondary	Prevalence of rhinosinusitis	To analyse demographic data in conscripts with rhinosinusitis	Through data collection, an average of 1 week
Secondary	Prevalence of human papilloma virus vaccines	To assess the prevalence of HPV vaccines among conscripts at the military induction board	Through data collection, an average of 1 week
Secondary	Prevalence of human papilloma virus vaccines	To assess knowledge about HPV and HPV vaccinations and in dependent of that prevalence of HPV vaccines among conscripts at the military induction board	Through data collection, an average of 1 week
Secondary	Prevalence of hearing impairment	To assess the prevalence of hearing impairment in conscripts at the military induction board	Through data collection, an average of 1 week
Secondary	Prevalence of hearing impairment	To assess the difference in prevalence of subjective symptoms of hearing impairment compared to objective (apparatus based and laboratory based) signs of hearing impairment	Through data collection, an average of 1 week
Secondary	Prevalence of hearing impairment	To analyse demographic data in conscripts with hearing impairment	Through data collection, an average of 1 week
Secondary	Prevalence of long-COVID	To assess the prevalence of long-COVID in conscripts at the military induction board	Through data collection, an average of 1 week
Secondary	Prevalence of long-COVID	To assess different symptoms of long-COVID in conscripts at the military induction board	Through data collection, an average of 1 week
Secondary	Prevalence of COVID-19 infection	To assess the prevalence of previous COVID 19 infections in conscripts at the military induction board	Through data collection, an average of 1 week
Secondary	Prevalence of long-COVID	To analyse demographic data in conscripts with long-COVID	Through data collection, an average of 1 week