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NCT04382846 Clinical Trial

Novel Regimens in COVID-19 Treatment

COVID Clinical Trial

Official title:
Nitazoxanide in Treatment of COVID-19

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04382846
Other study ID # tanta covid treatment
Secondary ID
Status Recruiting
Phase Phase 3
First received
Last updated
Start date May 8, 2020
Est. completion date December 1, 2030

Study information
Verified date December 2020
Source Tanta University
Contact Sherief Abd-Elsalam, ass. prof.
Phone 00201147773440
Email sheriefabdelsalam@yahoo.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Nitazoxanide has been shown to have a clinical efficacy against severe acute respiratory syndrome coronavirus 2; ivermectin has also demonstrated a remarkable experimental efficacy with a potential to be used for Coronavirus disease 2019.

Description:

Nitazoxanide has been shown to have a clinical efficacy against severe acute respiratory syndrome coronavirus; ivermectin has also demonstrated a remarkable experimental efficacy with a potential to be used for Coronavirus disease 2019. Some studies demonstrated the efficacy of combined regimen of nitazoxanide and azithromycin or ivermectin and chloroquine.

Recruitment information / eligibility
Status Recruiting
Enrollment 160
Est. completion date December 1, 2030
Est. primary completion date December 1, 2030
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Patients with COVID-19 infection Exclusion Criteria: - Allergy or contraindication to the drugs.

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Nitazoxanide
Nitazoxanide

Locations
Country Name City State
Egypt Sherief Abd-Elsalam Tanta
Egypt Tanta University, Assiut University Tanta

Sponsors (1)
Lead Sponsor Collaborator
Tanta University

Country where clinical trial is conducted

Egypt, 

References & Publications (2)

Choudhary R, Sharma AK. Potential use of hydroxychloroquine, ivermectin and azithromycin drugs in fighting COVID-19: trends, scope and relevance. New Microbes New Infect. 2020 Apr 22;35:100684. doi: 10.1016/j.nmni.2020.100684. eCollection 2020 May. Review. — View Citation

Kelleni MT. Nitazoxanide/azithromycin combination for COVID-19: A suggested new protocol for early management. Pharmacol Res. 2020 Jul;157:104874. doi: 10.1016/j.phrs.2020.104874. Epub 2020 Apr 30. — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Number of patients with virological cure the number of patients with virological cure 6 months
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