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NCT ID: NCT00442312 Active, not recruiting - Glaucoma Clinical Trials

Combigan Ophthalmic Solution(Brimonidine 0.2% and Timolol 0.5%)With Latanoprost Compared With Latanoprost Monotherapy

Start date: May 2006
Phase: Phase 4
Study type: Interventional

This study is to evaluate the efficacy and safety of Combigan ophthalmic solution in combination with Latanoprost when the therapy is swiched from Latanoprost monotherapy in patient with Glaucoma or ocular hypertension. Hypothesis: 1. Combigan Ophthalmic Solution provides addition IOP loweringwhen combined with Latanoprost. 2. The treatment with Combigan Ophthalmic Solution has an acceptable safety profile, as measured by ocular and systemic safety parameters.

NCT ID: NCT00415337 Active, not recruiting - Lung Neoplasms Clinical Trials

Endobronchial Ultrasound Guided Transbronchial Lung Biopsy With or Without Guide Sheath in Lung Tumors and the Analysis of Echoic Patterns of Lung Tumors and Mediastinal Lymph Nodes, and the Association Between Diagnostic Yield of Transbronchial Lung Biopsy and EBUS Echoic Features.

Start date: April 2007
Phase: N/A
Study type: Observational

1. Endobronchial ultrasonography (EBUS) is useful in localizing peripheral lung lesions. The EBUS, further combined with the guide sheath (GS) technique, has been reported to increase the yield of transbronchial biopsy. However, there are no reports comparing the GS technique and the traditional EBUS technique in diagnosing the peripheral lung tumor. 2. Previous reports have revealed that several characteristic echoic patterns correlate well with the histopathological findings of benign and malignant lesions. Therefore, EBUS may also be useful in the differential diagnosis of malignant lesions of the lung.

NCT ID: NCT00399035 Active, not recruiting - Clinical trials for Metastatic Colorectal Cancer

Cediranib (AZD2171, RECENTIN™) in Addition to Chemotherapy in Patients With Untreated Metastatic Colorectal Cancer

HORIZON II
Start date: November 2006
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if Cediranib when added to chemotherapy is more effective than chemotherapy alone in prolonging life expectancy and slowing disease progression in patients with previously untreated metastatic colorectal cancer.

NCT ID: NCT00329888 Active, not recruiting - Choledocholithiasis Clinical Trials

Comparison of Papillary Balloon Dilatation Vs.Sphincterotomy for Lithotripsy in Difficult Sphincterotomy or Distal CBD Tapering

Start date: March 2006
Phase: N/A
Study type: Observational

Compare endoscopic papillary balloon dilatation vs. endoscopic sphincterotomy for bile duct stones in: - when sphincterotomy is difficult (periampullary diverticulum, prior sphincterotomy or Billroth II anastomosis) - when there is distal CBD tapering.

NCT ID: NCT00294658 Active, not recruiting - Myasthenia Gravis Clinical Trials

Thymectomy Trial in Non-Thymomatous Myasthenia Gravis Patients Receiving Prednisone Therapy

Start date: June 2006
Phase: Phase 3
Study type: Interventional

The purpose of this trial is to determine if thymectomy combined with prednisone therapy is more beneficial in treating non-thymomatous myasthenia gravis than prednisone therapy alone.

NCT ID: NCT00262171 Active, not recruiting - Clinical trials for Hereditary Nonpolyposis Colorectal Cancer

Hereditary Nonpolyposis Colorectal Cancer in Taiwan-Related Genetic Study and Clinical Applications

Start date: May 2002
Phase: N/A
Study type: Observational

The purpose of this study is to establish the HNPCC related information in Taiwan, and to characterize relevant susceptibility genes related to colorectal cancer to provide better disease control for the high-risk people. To accomplish this objective, we will collect detailed information of the HNPCC patients and their families from the collaborative hospitals and relate the information to the risk of CRC in order to provide sound disease control system in Taiwan.

NCT ID: NCT00262067 Active, not recruiting - Clinical trials for Metastatic Breast Cancer

A Study Evaluating the Efficacy and Safety of Bevacizumab in Combination With Chemotherapy in Untreated Metastatic Breast Cancer (RIBBON 1)

Start date: December 2005
Phase: Phase 3
Study type: Interventional

This is a Phase III, multicenter, randomized, placebo-controlled trial designed to evaluate the efficacy and safety of bevacizumab in combination with chemotherapy compared with chemotherapy alone in subjects with previously untreated metastatic breast cancer.

NCT ID: NCT00260871 Active, not recruiting - Lung Cancer Clinical Trials

Genetic Epidemiological Study of Lung Cancer in Taiwan and Clinical Applications

Start date: May 2002
Phase: N/A
Study type: Observational

Lung adenocarcinoma in Chinese females is hypothesized to be determined by both genetic and environmental factors. In this grant proposal, we propose to map the loci of susceptibility genes of female lung adenocarcinoma based on multiplex families recruited in Taiwan. We focus on a unique pathological type of a unique population in order to reduce heterogeneity of the genetic background. Compared with western women, female Chinese population has a high prevalence of lung adenocarcinoma. Our reasoning is that if we focus on a specific sub-type, which has a familial basis, we will increase the probability of identifying genes associated with female lung adenocarcinoma. The primary goal of this study is to identify the genetic and environmental determinants of female lung adenocarcinoma, and study the relationship between gene polymorphisms and clinical manifestation profiling of lung cancer.

NCT ID: NCT00247507 Active, not recruiting - Anemia Clinical Trials

The Effects of Acetylcysteine on Alleviating Damage of Oxidative Stress in Hemodialysis Patients

Start date: September 2005
Phase: Phase 4
Study type: Interventional

The aim of this study is to explore and identify the effects of acetylcysteine, a common mucolytic with anti-oxidant property, on alleviating the damage caused by increased oxidative stress in hemodialysis patients.

NCT ID: NCT00207974 Active, not recruiting - Clinical trials for Hyperuricemia, Anserine, Pharmacokinetic

Pharmacokinetic Study of Marine Active in Health Men

Start date: n/a
Phase: Phase 1
Study type: Interventional

Hyperuricemia is often associated with metabolic syndrome, which is a known precursor of atherosclerosis. The Yaizu Suisankagaku Industry Company have developed industrial production, named Marine Active. Human clinical trials showed reduction of creatine phosphokinase activity and sero-uric acid. Randomize, double blind clinical trial is entrust to our hospital. This study design is blood sampling from the health men who take 1 gm of marine active to analyse the pharmacokinetics of anserine.