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NCT ID: NCT04296422 Enrolling by invitation - Clinical trials for Premenstrual Syndrome

Different Does of Acupuncture on Premenstrual Syndrome Efficacy Analysis

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

The design of the study includes 3 groups for women with premenstrual syndrome, 1low dose acupuncture in the low-dose group, 2 high dose acupuncture in the high-dose group, and 3 the drug group (contraceptives) . Serum marker change of PGE2, CA125, E2, and progesterone in enrolled patients will be measured before and after treatment, along with VAS and MDQ questionnaires. The treatment efficacy of different groups and the relationship between PMS and patients TCM syndrome pattern will also be recorded and estimated.

NCT ID: NCT04284917 Enrolling by invitation - Clinical trials for Propionic Acidemia (PA) , Methylmalonic Acidemia (MMA)

Long-term Efficacy of Carglumic Acid in Organic Acidemia.

Start date: November 28, 2019
Phase: N/A
Study type: Interventional

Evaluate the Long Term Effectiveness & Safety of the use of Carglumic Acid (Carbaglu®) in Patients with Propionic Acidemia (PA) or Methylmalonic Acidemia (MMA).

NCT ID: NCT04255797 Enrolling by invitation - Premature Birth Clinical Trials

Effects of Baby Massage on Parenting Stress and Attachment in Premature

Start date: March 30, 2020
Phase: N/A
Study type: Interventional

This study is an experimental randomized controlled clinical trial. To explore the effect of infant massage on parental pressure and parent-child attachment of premature infants. The intervention time was from 5 days after birth to discharge from premature infants. Data were collected at five time points in longitudinal, before massage (T0), one week (T1), four weeks (T2), and eight weeks ( T3), 12 weeks (T4). Parents in the experimental group were given massage interventions when visiting premature babies, while parents in the control group visited premature babies as usual and contacted premature babies according to general nursing instructions.

NCT ID: NCT04250103 Enrolling by invitation - Clinical trials for Health Care Utilization

Home-based Longitudinal Investigation of the Multidisciplinary Team Integrated Care

HOLISTIC
Start date: November 20, 2019
Phase:
Study type: Observational

Some research found the effectiveness of implementation of home health care on patients' physical function, quality of life (QoL) and decreased the risk of hospitalization and medical costs. However, little was known about the longitudinal change of comprehensive assessments of physical and mental health, QoL, well-being, and medical resource utilization of patients receiving home health care and their caregivers. Furthermore, the evaluation of advance care planning, palliative care need, and the quality of dying and death were also insufficient among the aforementioned population. Therefore, this cohort study aims to investigate the longitudinal change of health-related outcomes and utilization of resource utilization, and explore their trajectories in two years for patients who receive home health care and their caregivers in Taiwan.

NCT ID: NCT04249570 Enrolling by invitation - Infection Clinical Trials

Efficacy of Gastrostomy Tube Coated With Povidone-iodine for Reducing Peristomal Infection Rate After PEG Insertion

Start date: April 2014
Phase: N/A
Study type: Interventional

Percutaneous endoscopic gastrostomy (PEG) was created to replace surgical gastrostomy in patients who are needed long-term tube feeding. PEG has less severe complication rate or mortality rate compared with traditional surgical gastrostomy. However, there are still some mild complications which cannot be completely prevented and peristomal infection is the most common one. Povidone-iodine (PVP-I) exhibits broad range of microbicidal activity via increasing the solubility of iodine. In our study, the gastrostomy feeding tube will be coated with a layer of Betadine before PEG technique. Investigators expect gastrostomy feeding tube coated with Betadine will reduce the oropharyngeal, esophageal and gastric bacteria colonization rate, followed by reducing peristomal infection rate.

NCT ID: NCT04201314 Enrolling by invitation - Hyperlipidemia Clinical Trials

Effect of InnoSlim® on Blood Sugar and Blood Lipids Regulation in Humans

Start date: November 8, 2019
Phase: N/A
Study type: Interventional

InnoSlim® has been studied for enhancing metabolic functions whereas many lab studies have demonstrated the potential efficacy of InnoSlim® for the blood sugar and blood lipids regulation. There has been no relevant human study on InnoSlim® on blood sugar and blood lipids regulation. There have reported that 2018 estimating the total costs of diagnosed diabetes have risen to $327 billion in 2017 from $245 billion in 2012. Although pharmacological methods have been developed to treat diabetes, these treatments can be costly and are not without potential adverse effects. The development of dietary agents for the prevention of diabetes could represent a cost-effective and safe means to deal with this growing public health crisis.

NCT ID: NCT04185129 Enrolling by invitation - Asthma Clinical Trials

Comparison Efficacy in Patients With Asthma Using Foster MDI and Relvar Medications

Start date: January 1, 2020
Phase: Phase 4
Study type: Interventional

This is a randomized study to compare asthma patients using Foster or Relvar.

NCT ID: NCT04164199 Enrolling by invitation - Clinical trials for Advanced Malignancies

Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With Advanced Malignancies

Start date: December 19, 2019
Phase: Phase 3
Study type: Interventional

This is an open-label, multicenter, extension study to evaluate the long-term safety and efficacy of BeiGene investigational drugs in participants with advanced malignancies who participated in a prior BeiGene-sponsored clinical study (parent study).

NCT ID: NCT04118400 Enrolling by invitation - Clinical trials for Respiratory Distress Syndrome in Premature Infant

Ventilator Weaning Outcome Between NIV-NAVA and Nasal CPAP (or IMV ) Modes in Premature Neonates

Start date: October 31, 2019
Phase:
Study type: Observational [Patient Registry]

Premature neonates are prone to respiratory distress and need ventilator support because of the rapid breathing and large variations in respiratory patterns. The setting and adjustment of the ventilator for premature neonate is not easy, often resulting in poor patient-ventilator interaction, increased work of breathing, patient discomfort and delayed weaning . Recently, a new ventilation mode (NAVA; Neurally Adjusted Ventilatory Assist) mode, allows the respirator to provide a proportional ventilation mode based on the patients' diaphragm electrical activity, which was validated in many domestic and international clinical researches. The NAVA mode improves patient-ventilator interaction, reduces work of breathing and contributes to early weaning and extubation . When participating in this study, the neonate with receive a special oral tube placement, which is used to replace the original gastric tube to monitor the electrical activity of the diaphragm.

NCT ID: NCT04042532 Enrolling by invitation - Clinical trials for Alzheimer Disease, Early Onset

Theta-burst Stimulation on Cognitive Function in the Patients With Young-onset Alzheimer's Disease Dementia

Start date: January 3, 2020
Phase: N/A
Study type: Interventional

Young-onset dementia (YOD) is a devastating condition, and it produces substantial psychosocial impacts on individual's functioning and family's care burden. Alzheimer's disease (AD) dementia is the most common type in YOD. Medication treatment Response was limited and unsatisfactory. In recent years, repetitive transcranial magnetic stimulation (rTMS) has been considered an alternative for the improvement of cognition in older patients with cognitive impairment. This study aims to examine the effects and potential mechanisms of theta-burst stimulation (TBS) on cognitive function in individuals with young-onset AD.