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NCT ID: NCT06028438 Active, not recruiting - Clinical trials for Arthritis, Rheumatoid

A Study to Evaluate the Nipocalimab and Certolizumab Combination Therapy in Participants With Active Rheumatoid Arthritis

DAISY
Start date: August 15, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy of combination therapy with nipocalimab and certolizumab compared to certolizumab monotherapy.

NCT ID: NCT05916365 Active, not recruiting - Atopic Dermatitis Clinical Trials

Long-term Safety and Efficacy of Lebrikizumab in Adult and Adolescent Participant With Moderate-to-Severe Atopic Dermatitis

ADlong
Start date: May 23, 2023
Phase: Phase 3
Study type: Interventional

The main purpose of the study is to assess the long-term tolerability and effectiveness of lebrikizumab in adult and adolescent participants with moderate-to-severe atopic dermatitis (AD). Participants who complete the last assessment visit in ADjoin (Week 100) will be offered the opportunity to enroll in this extension study.

NCT ID: NCT05910528 Active, not recruiting - Crohn Disease Clinical Trials

RVT-3101 for the Treatment of Moderate to Severe Active Crohn's Disease

Start date: July 24, 2023
Phase: Phase 2
Study type: Interventional

This Phase 2, randomized, double-blind, multicenter, induction and maintenance study is designed to evaluate the safety and efficacy of RVT-3101 in adult participants with moderate to severe active Crohn's disease.

NCT ID: NCT05906628 Active, not recruiting - Hand Eczema Clinical Trials

Topical Ruxolitinib Evaluation in Chronic Hand Eczema

Start date: July 31, 2023
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in adult participants with diagnosis of chronic hand eczema (CHE) and moderate to severe disease activity (Investigator's Global Assessement (IGA) of CHE score 3 or 4).

NCT ID: NCT05905783 Active, not recruiting - Clinical trials for Hidradenitis Suppurativa

Hidradenitis Suppurativa Study of Izokibep

Start date: June 22, 2023
Phase: Phase 3
Study type: Interventional

Izokibep is a small protein molecule that acts as a selective, potent inhibitor of interleukin 17A, to which it binds with high affinity. This study investigates izokibep in subjects with active Hidradenitis Suppurativa (HS), including tumor necrosis factor-alpha inhibitor (TNFi) naïve subjects, and those who had an inadequate response or intolerance to TNFi, or for whom TNFi is contraindicated.

NCT ID: NCT05903300 Active, not recruiting - Clinical trials for Musculoskeletal Pain

Validation of the Polish Version of the MPIIQM Questionnaire for Musicians

Start date: April 17, 2023
Phase:
Study type: Observational

The aim of this study, originally named "Cross-Cultural Adaptation and Validation of the Musculoskeletal Pain Intensity and Interference Questionnaire for Musicians of the Polish Population (MPIIQM-P)" is the enlargement of validation of the Polish questionnaire.

NCT ID: NCT05896527 Active, not recruiting - Plaque Psoriasis Clinical Trials

A Study to Evaluate the Efficacy and Safety of DC-806 in Participants With Moderate to Severe Plaque Psoriasis

Illuminate
Start date: May 11, 2023
Phase: Phase 2
Study type: Interventional

This is a 12-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging study to evaluate the efficacy and safety of DC-806 in participants with moderate to severe plaque psoriasis. This study will evaluate the efficacy, safety, tolerability, and pharmacokinetics (PK) of multiple oral doses of DC-806 in participants with moderate to severe plaque psoriasis.

NCT ID: NCT05879107 Active, not recruiting - Clinical trials for Respiratory Syncytial Virus Infections

Study to Assess the Immune Response, the Safety and the Reactogenicity of Respiratory Syncytial Virus (RSV) Prefusion Protein 3 Older Adult (OA) (RSVPreF3 OA) Investigational Vaccine When co Administered With PCV20 in Older Adults

Start date: May 26, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the ability of RSVPreF3 OA investigational vaccine to generate an immune response when given in combination with PCV20 and its safety in older adults, aged ≥60 years of age.

NCT ID: NCT05853354 Active, not recruiting - Clinical trials for Osteoporosis, Postmenopausal

Comparative Efficacy, Safety, PK, and Immunogenicity Study

Start date: April 5, 2023
Phase: Phase 3
Study type: Interventional

this comparative clinical study is designed to demonstrate that LY06006 and EU-Prolia have no clinically meaningful differences in clinical efficacy, pharmacodynamic (PD), safety, PK, and immunogenicity in postmenopausal women with osteoporosis.

NCT ID: NCT05849922 Active, not recruiting - Clinical trials for Hidradenitis Suppurativa

A Study to Test the Efficacy and Safety of SAR442970 in Adults With Hidradenitis Suppurativa

HS OBTAIN
Start date: June 6, 2023
Phase: Phase 2
Study type: Interventional

This is a Phase 2 study in adult participants with moderate to severe hidradenitis suppurativa (HS). The purpose of the study is to evaluate the efficacy and safety of SAR442970 compared to placebo.