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NCT ID: NCT05926440 Withdrawn - COVID-19 Clinical Trials

Immunogenicity and Safety Study of SCB-2023 Vaccine as a Booster in Adults

Start date: August 17, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the immunogenicity and safety of SCB-2023 trivalent vaccine compared to the prototype SCB-2019 monovalent vaccine in participants previously vaccinated with 3 doses of inactivated COVID-19 vaccine ≥6 months prior to enrollment.

NCT ID: NCT04364815 Withdrawn - COVID-19 Clinical Trials

The University of the Philippines Hydroxychloroquine PEP Against COVID-19 Trial

Start date: December 2020
Phase: Phase 3
Study type: Interventional

This COVID-19 pandemic warrants urgent strategies to protect people at high risk of infection, particularly the healthcare workers. Secondary prevention through post-exposure prophylaxis (PEP) and early treatment of infection are needed to prevent severe cases and cut secondary transmission. Hydroxycholoroquine (HCQ) is an inexpensive anti-malarial drug with immunomodulatory effects that are currently used as an off-label treatment for symptomatic COVID-19 patients. In vitro studies have shown that it can efficiently inhibit SARS-CoV-2 infection and has potential as a post-exposure prophylaxis drug.

NCT ID: NCT02392676 Withdrawn - Clinical trials for Platinum Sensitive Relapsed Ovarian Cancer

Olaparib Maintenance Treatment Versus Placebo in Patients With PSR Ovarian Cancer Who Are in CR or PR to Platinum-based Chemotherapy and Whose Tumours Carry sBRCAm or HRR-associated Genes Mutations

Start date: July 2016
Phase: Phase 3
Study type: Interventional

Olaparib administered as monotherapy in the maintenance setting improves progression free survival compared to placebo in patients whose tumours carry loss of function (deleterious or suspected deleterious) somatic BRCA mutations or loss of function (deleterious or suspected deleterious) mutation in non-BRCA Homologous Recombination Repair (HRR) -associated genes who have a complete or partial response to platinum-based chemotherapy.

NCT ID: NCT02241174 Withdrawn - Atopic Dermatitis Clinical Trials

0.005% Sodium Hypochlorite Final Rinse Solution in Atopic Dermatitis

Start date: July 2014
Phase: Phase 1
Study type: Interventional

This study will determine the safety and efficacy of diluted bleach bath solution as final rinse on the reduction of Staphylococcus aureus colonization among children and adult Filipinos with mild to moderate atopic dermatitis..

NCT ID: NCT01885611 Withdrawn - Hansen's Disease Clinical Trials

Virgin Coconut Oil Oral Supplementation for Leprosy Patients

Start date: June 2013
Phase: Phase 1/Phase 2
Study type: Interventional

To date, there has been no clinical investigation on the effects of virgin coconut oil (VCO) oral supplementation on patients with Hansen's disease (HD) undergoing medical treatment. This study aims to examine the possible protective effect of exogenous supplementation of VCO on the oxidative stress, antioxidant status, and treatment response among HD patients. Treatment response will be defined as the clinical changes in cutaneous and neurologic manifestations as measured by the clinical response score. This study also aims to investigate the potential of VCO as an adjunct to Multi-Drug Therapy (MDT) in mitigating lepra reactions.

NCT ID: NCT01692132 Withdrawn - Clinical trials for Chronic Constipation

A Post Marketing Surveillance Study on the Safety and Effectiveness of Prucalopride in the Treatment of Chronic Constipation

Start date: February 2013
Phase: Phase 4
Study type: Observational

The purpose of this study is to determine the safety and effectiveness of prucalopride in the treatment of Filipino patients with chronic constipation whom prior laxatives fail to provide adequate relief.

NCT ID: NCT01600963 Withdrawn - Clinical trials for Multi-drug Resistant Tuberculosis

A Study to Evaluate the Efficacy and Safety of TMC207 in Patients With Pulmonary Infection With Multi-drug Resistant Mycobacterium Tuberculosis

Start date: March 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to provide safety and efficacy data for TMC207 and to demonstrate that TMC207 added to a background regimen (BR) is superior to treatment with the BR plus placebo.

NCT ID: NCT01219114 Withdrawn - Clinical trials for Complicated Skin and Skin Structure Infections and Bacteremia Including Right-sided Endocarditis

Safety and Efficacy Study of CUBICIN (Daptomycin) Under Conditions of Actual Use

Start date: October 2010
Phase: N/A
Study type: Observational

The purpose of this study is to monitor the safety and efficacy of CUBICIN under conditions of actual use in patients who are diagnosed with complicated Skin and Skin Structure infection (cSSI) or Staphylococcus aureus bacteria including right-sided endocarditis and are prescribed CUBICIN by their physician.