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NCT ID: NCT04849624 Recruiting - Covid19 Clinical Trials

Body Composition Study in Critically Ill Patients-Extended to COVID-19

COVID-MUSCLE
Start date: March 5, 2021
Phase:
Study type: Observational

Muscle loss (ultrasound quadricep muscle) and muscle strength (handgrip and knee extension strength) will be compared between COVID-19 and non COVID-19 critically ill patients.

NCT ID: NCT04843865 Not yet recruiting - Breast Cancer Clinical Trials

A Systemic Approach to Study the Traditional Chinese Medicine as an Adjuvant Treatment in Breast Cancer Patients

Start date: June 2021
Phase: N/A
Study type: Interventional

Chinese herbs can alleviates the side effects caused by conventional treatment in breast cancer patients and affects the syndrome element differentiation by altering the specific set of proteomes at specific time point of treatment.

NCT ID: NCT04836234 Recruiting - Orthodontic Pain Clinical Trials

Chewing Gum Effect in Reducing Orthodontic Pain After Separator and Initial Arch Wire Placement

Start date: March 6, 2019
Phase: N/A
Study type: Interventional

Pain is the most claimed complaint from orthodontic treatment. Fear of pain has contributed to patients' avoidance of seeking orthodontic treatment, affects patients' compliance to treatment and even becomes the main reason for discontinuing orthodontic treatment. For years, orthodontic patients have reported using analgesics during orthodontic treatment to ease the pain. However, analgesics have many side effects such as allergic reactions, bleeding disorders, gastric ulcers, liver toxicity and their potential influence in slowing down tooth movement. This study aimed to investigate the effectiveness of chewing gums in pain reduction in Malaysian multi-ethnic orthodontic patients and to explore the possibility of chewing gum to be recommended as a suitable substitute for analgesics in our future practice.

NCT ID: NCT04833595 Recruiting - Clinical trials for Cholesterol; Lipidosis

Can Mindful Eating Improve Cholesterol and Glucose Level

Start date: March 29, 2021
Phase: N/A
Study type: Interventional

This study aims to explore the effectiveness of mindful eating and its effect on cholesterol and glucose level. The participants will be required to get tested for their fasting total cholesterol and blood glucose level for two times. At the first visit, they will be required to complete the survey given and be tested for their fasting total cholesterol and blood glucose level. A recommendation on healthy food intake will be sent to participants. At the end of each week, participants will be required 1) to submit THREE photos of the meals that they are most satisfied with in terms of healthiness and 2) using the photos to answer a questionnaire about their diet. The photos and completed questionnaire must be submitted to the research investigator each week for a total of 8 weeks. After 8 weeks, participants will be required to get tested for their fasting total cholesterol and blood glucose level in the appointed pharmacy for the second time. It is estimated to require 15-30 minutes of their time weekly.

NCT ID: NCT04833166 Recruiting - Clinical trials for Airway Complication of Anesthesia

Comparing Full vs. Partial Glottis View Using CMAC D-Blade Video Laryngoscope in Simulated Cervical Injury Patient

Start date: February 25, 2021
Phase: N/A
Study type: Interventional

Direct laryngoscope requires proper alignment of the oro-pharyngeal-laryngeal axis to provide an optimal glottic view for intubation. However, in cervical spine patients, this alignment is not possible thus resulting in an increased risk of fail intubations. D-blade comes with an elliptically tapered blade shape rising at the distal end to provide better glottic visualization in comparison with direct laryngoscopes. Hence, CMAC D-blade is preferred in simulated cervical spine injury where intubator needs to maintain a neutral neck position. However, intubation time may be significantly longer due to difficulty in negotiating the endotracheal tube pass vocal cord and impingement of endotracheal tube to the anterior wall of trachea. There is a study published Glidescope which is also a hyperangulated videolaryngoscope suggested that obtaining a partial glottic view of larynx may facilitate a faster and easier tracheal intubation when compare to a full glottis view. The aim of this study is to clinically evaluate the time of tracheal intubation in relation to the full glottic view vs. partial glottic view which is deliberately obtained when using CMAC D-blade video laryngoscopy in simulated cervical spine injury.

NCT ID: NCT04832984 Not yet recruiting - PreDiabetes Clinical Trials

Prevention and Treatment of Diabetes in Adults

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

Currently, an estimated 3.9 million Malaysians continue to live with diabetes with many more who live with prediabetes. Diabetes was the one of the leading causes of death in the Malaysia and the leading cause for kidney failure, lower-limb amputations, and adult-onset blindness. Heart disease and stroke are two to four times more likely for individuals with diabetes. The use of mHealth or mobile health application can reduce blood sugar among individuals with prediabetes but also prevent a later occurrence of diabetes. In this study, the investigators aim to develop and evaluate the effectiveness of a digital health supported pre-diabetes management program based in an urban community pharmacy setting

NCT ID: NCT04829045 Not yet recruiting - Clinical trials for Diabetes Mellitus, Type 2

Effects of Acupuncture as Adjunctive Therapy in Patients With Type 2 Diabetes Mellitus

Start date: May 2021
Phase: N/A
Study type: Interventional

This study aims to determine the effect of acupuncture as an adjunctive therapy on homeostasis model assessment-insulin resistance (HOMA-IR) and health-related quality of life (HRQoL) in patients with type 2 diabetes mellitus.

NCT ID: NCT04824846 Not yet recruiting - Quality of Life Clinical Trials

Low Back Pain and Quality of Life Among the Ambulance Drivers in Malaysia's Hospitals

Start date: July 2021
Phase: N/A
Study type: Interventional

The study is a community interventional study by using an integrated back pain module (IBPM). The purpose of this study is to find out if the module training has any benefit on Low Back pain among ambulance drivers. The effectiveness of the module is determined by baseline quality of life results compared with after the intervention program completed.

NCT ID: NCT04824092 Not yet recruiting - Clinical trials for Diffuse Large B-cell Lymphoma

Tafasitamab + Lenalidomide + R-CHOP Versus R-CHOP in Newly Diagnosed High-intermediate and High Risk DLBCL Patients

frontMIND
Start date: April 2021
Phase: Phase 3
Study type: Interventional

This is a phase 3, multicenter, randomized, double-blind, placebo-controlled trial designed to compare the efficacy and safety of the humanized monoclonal anti CD19 antibody tafasitamab plus lenalidomide in addition to R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) versus R-CHOP in previously untreated, high-intermediate and high-risk patients with newly-diagnosed DLBCL

NCT ID: NCT04822714 Completed - Competence Clinical Trials

Effectiveness of Mobile-phone Career Competencies Intervention for Malaysian Public Sector Managers

Start date: August 3, 2020
Phase: N/A
Study type: Interventional

This study aims to evaluate the effectiveness of a user and expert centric mobile phone-based career intervention program of career competencies among Malaysian public managers.