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NCT ID: NCT05205343 Recruiting - Clinical trials for GastroEsophageal Cancer

Trans-Pacific Multicenter Collaborative Study of Minimally Invasive Proximal Versus Total Gastrectomy for Proximal Gastric and Gastroesophageal Junction Cancers

Start date: May 11, 2022
Phase:
Study type: Observational

To compare the symptoms of patients who have a MIPG to the symptoms of patients who have a MITG.

NCT ID: NCT05203172 Recruiting - Solid Tumors Clinical Trials

The FLOTILLA Study: Providing Continued Access to The Study Medicines Encorafenib and Binimetinib for Participants in Prior Clinical Trials

Start date: July 5, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this clinical trial (called the FLOTILLA study) is to give continued access to the study medicines, as well as safety follow-up, for participants in prior clinical trials of encorafenib and/or binimetinib. All participants who took part in earlier encorafenib and/or binimetinib studies may participate the FLOTILLA study if they are still benefiting from the use of the study medicines. This will be determined by the study doctor. People may not participate in the FLOTILLA study if they have not enrolled in a prior study of encorafenib or binimetinib. Participants that had enrolled but had stopped receiving the study treatment in a prior study cannot enrolled in this study. Participants in the FLOTILLA study will receive encorafenib and/or binimetinib at the same dose and frequency as in their prior study, for up to about 5 years.

NCT ID: NCT05202262 Recruiting - Asthma Clinical Trials

A 24-Week Efficacy and Safety Study to Assess Budesonide and Formoterol Fumarate Metered Dose Inhaler in Adult and Adolescent Participants With Inadequately Controlled Asthma (VATHOS)

VATHOS
Start date: January 12, 2022
Phase: Phase 3
Study type: Interventional

This is a 24 week study to evaluate the efficacy and safety of budesonide and formoterol fumarate metered dose inhaler in adults and adolescents with inadequately controlled asthma.

NCT ID: NCT05201781 Recruiting - Multiple Myeloma Clinical Trials

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

Start date: March 9, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to collect long-term follow-up data on delayed adverse events after administration of ciltacabtagene autoleucel (cilta-cel), and to characterize and understand the long-term safety profile of cilta-cel.

NCT ID: NCT05198557 Recruiting - Systemic Sclerosis Clinical Trials

A Study of MT-0551 in Patients With Systemic Sclerosis

Start date: July 20, 2022
Phase: Phase 3
Study type: Interventional

The study will verify the superiority of MT-0551 to placebo at 26 weeks after treatment initiation in systemic sclerosis (SSc) patients using the modified Rodnan Total Skin thickness Score (mRTSS) as a measure of skin thickening. The safety and pharmacokinetics will also be investigated.

NCT ID: NCT05197426 Recruiting - Clinical trials for Acute Myeloid Leukemia

A Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Best Supportive Care as Maintenance Therapy in Japanese Participants With Acute Myeloid Leukemia (AML) in Complete Remission

Start date: January 17, 2022
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of oral azacitidine plus best supportive care versus best supportive care as maintenance therapy in a cohort of Japanese participants ≥ 55 years of age with Acute Myeloid Leukemia (AML) and in complete remission/complete remission with incomplete blood count recovery after conventional induction chemotherapy with or without consolidation chemotherapy.

NCT ID: NCT05193136 Recruiting - COPD Clinical Trials

Sleep Hygiene, Sarcopenia, and Cognitive Function in Respiratory Disease

Start date: December 10, 2021
Phase:
Study type: Observational

We aim to clarify the relationship between sleep hygiene and the onset of sarcopenia or cognitive dysfunction using sleep time, arousal, and sleep quality as indicators in COPD or IPF patients, and clarify the effects of sleep hygiene on disease progression and life prognosis.

NCT ID: NCT05192174 Recruiting - Solid Tumor Clinical Trials

Study of NIB101 in Participants With Advanced Solid Tumors

Start date: January 24, 2022
Phase: Phase 1
Study type: Interventional

NIB101-01 study is an open-label, non-randomized Phase 1 study in participants with GM2 positive advanced solid tumor, who failed to available standard of cares to evaluate the safety and tolerability of NIB101.

NCT ID: NCT05188976 Recruiting - Respiratory Disease Clinical Trials

Assessment of End-tidal Carbon Dioxide Levels in Respiratory Disease

Start date: December 1, 2021
Phase:
Study type: Observational

The investigators aim to evaluate the correlation between PetCO2, PaCO2, and PtcCO2 in patients with respiratory diseases. The investigators also evaluate the correlation between PetCO2, PaCO2, and PtcCO2 changes over time.

NCT ID: NCT05183984 Recruiting - Ovarian Cancer Clinical Trials

Niraparib With beVAcizumab After Complete cytoreductioN in Patients With ovArian Cancer

NIRVANA-1
Start date: February 1, 2022
Phase: Phase 2
Study type: Interventional

Randomized, open label, phase II multicenter study to assess the efficacy niraparib versus niraparib +bevacizumab maintenance in patients with newly diagnosed stage IIIA/B/C high-grade epithelial ovarian cancer with no residual disease after frontline surgery and treatment by adjuvant platinum-basedchemotherapy +/-bevacizumab.