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NCT ID: NCT02446379 Withdrawn - Pancreatic Cancer Clinical Trials

Use of the EnLightTM and LightPathTM Imaging Systems in Gastrointestinal Tumour Surgery

CLIO
Start date: n/a
Phase: N/A
Study type: Observational

This study will evaluate the performance of the EnLightTM and LightPathTM Imaging Systems in detecting tumour lesions in patients with gastric, pancreas, bile duct or duodenal cancer. EnLightTM will be used to detect positron emission and the LightPathTM system to detect Cerenkov Luminescence. Both are emitted by the Positron Emission Tomography (PET) agent. The study will also evaluate the patient safety and radiation safety of the EnLightTM, and the safety for the device operators and surgical staff of the LightPathTM Imaging System.

NCT ID: NCT02282176 Withdrawn - Clinical trials for Bronchopulmonary Dysplasia

TINN2: Treat Infection in NeoNates 2

TINN2
Start date: January 2015
Phase: Phase 3
Study type: Interventional

The aim of the TINN2 study is to evaluate the efficacy of azithromycin in prevention of bronchopulmonary dysplasia in preterm neonates.

NCT ID: NCT02015780 Withdrawn - Clinical trials for Type 2 Diabetes Mellitus

Fasiglifam in Type 2 Diabetic Subjects With Chronic Kidney Disease Stage 4 or 5 on Hemodialysis

Start date: December 2013
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy of fasiglifam 50 mg once daily compared to placebo on glycemic control as measured by glycosilated haemoglobin (HbA1c) over a 16-week treatment period in participants with Type 2 Diabetes Mellitus (T2DM) and chronic kidney disease (CKD) stage 4 or 5 on dialysis.

NCT ID: NCT01870284 Withdrawn - Clinical trials for Spondylitis, Ankylosing

Study of Ixekizumab in Participants With Active Ankylosing Spondylitis (AS)

SPIRIT A1
Start date: July 2014
Phase: Phase 3
Study type: Interventional

This study will assess the safety and efficacy of ixekizumab (LY2439821) compared to placebo in participants with active AS.

NCT ID: NCT01447394 Withdrawn - Clinical trials for Hepatitis C Virus (HCV)

Safety and Efficacy Study of Pegylated Interferon Lambda Versus Pegylated Interferon Alfa, Plus Ribavirin in Subjects With Hepatitis C

Start date: March 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if 48 weeks of therapy with Pegylated Interferon Lambda plus Ribavirin is effective and safe for a treatment of chronic hepatitis C (CHC) compared to therapy with Pegylated Interferon Alfa-2a plus Ribavirin.

NCT ID: NCT01441284 Withdrawn - Essential Tremor Clinical Trials

Efficacy of Pramipexole Extended Release in the Treatment of Essential Tremor

Start date: December 2017
Phase: Phase 3
Study type: Interventional

Aim of the study is to perform a double-blind, crossover, placebo-controlled multicenter study evaluating the efficacy of pramipexole on essential tremor.

NCT ID: NCT01205217 Withdrawn - Neoplasms, Breast Clinical Trials

Lapatinib or Trastuzumab Given Prior to Surgery With Chemotherapy in Patients With Early Breast Cancer

ELATE
Start date: December 2010
Phase: Phase 2
Study type: Interventional

This study will test the safety of a drug called lapatinib and how well it works. Lapatinib (also called Tyverb or Tykerb) will be compared with another drug trastuzumab (also called Herceptin). Trastuzumab is an antibody against the HER2 protein. It binds to part of the HER2 protein to stop it working. Clinical trials have found that adding trastuzumab to chemotherapy lowers the rate of cancer recurrence and improves survival in women with HER2 positive breast cancer. Lapatinib also stops the HER2 protein working and may slow or stop cancer cells from growing and may prevent cancer from returning. Lapatinib has been approved in some countries to treat patients with certain types of breast cancer. However lapatinib has not been approved to treat early breast cancer. This study is one of many being carried out involving lapatinib in early breast cancer and these studies are showing that it is a promising treatment. This study will compare lapatinib and trastuzumab. One group of people will take lapatinib and another group will take trastuzumab. The effects of the drugs, both good and bad, will be compared. This study will compare two different durations of HER2 treatment to see if earlier introduction of HER2 treatment is beneficial. The lapatinib group will receive HER2 treatment from the very beginning for 24 weeks prior to surgery and the trastuzumab group will only receive HER2 therapy for 12 weeks prior to surgery.

NCT ID: NCT00518921 Withdrawn - Clinical trials for Chronic Stable Angina

Capadenoson in Angina Pectoris

Start date: March 2008
Phase: Phase 2
Study type: Interventional

This is a multi-center and multi-national,randomized, double blind, placebo-controlled, 28-day treatment study with BAY 68-4986 taken orally or a matching placebo.

NCT ID: NCT00382837 Withdrawn - Clinical trials for Systemic Lupus Erythematosus

Study of Epratuzumab in Systemic Lupus Erythematosus

Start date: January 2007
Phase: Phase 3
Study type: Interventional

Epratuzumab is an investigational antibody designed to help treat SLE. The purpose is to evaluate safety and long term efficacy in concert with standard SLE treatments

NCT ID: NCT00349518 Withdrawn - Clinical trials for Acute Lymphoblastic Leukemia

Study of Dasatinib in Imatinib Resistant or Intolerant Subjects With Chronic or Advanced Phase CML or Philadelphia Chromosome Positive ALL

Start date: December 2006
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to further assess the safety of dasatinib in imatinib intolerant or resistant patients with chronic phase chronic myeloid leukemia, advanced phase chronic myeloid leukemia or Philadelphia chromosome positive acute lymphoblastic leukemia. The efficacy of the drug in this kind of patients will also further be documented.