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NCT ID: NCT02489227 Completed - Plaque Psoriasis Clinical Trials

Comparison of CHS-1420 Versus Humira in Subjects With Chronic Plaque Psoriasis

PsOsim
Start date: August 2015
Phase: Phase 3
Study type: Interventional

This is a 3-period study comparing CHS-1420 to Humira in patients with chronic plaque psoriasis.

NCT ID: NCT02480153 Completed - Clinical trials for Rheumatoid Arthritis

A Study Of PF-06410293 (Adalimumab-Pfizer) And Adalimumab (Humira®) In Combination With Methotrexate In Subjects With Active Rheumatoid Arthritis (REFLECTIONS B538-02).

Start date: June 25, 2015
Phase: Phase 3
Study type: Interventional

The study will assess the efficacy, safety, and immunogenicity of PF-06410293 and adalimumab in combination with methotrexate in subjects with moderately to severly active rheumatoid arthritis who have had an inadequate response to methotrexate. In an additional optional portion of the study, during open label Treatment Period 3 (TP3), a subset of subjects used a Prefilled Pen (PFP) to administer up to 3 injections of their study treatment (PF-06410293) at home.

NCT ID: NCT02477618 Completed - Clinical trials for Super-Refractory Status Epilepticus

A Study With SAGE-547 for Super-Refractory Status Epilepticus

Start date: June 2015
Phase: Phase 3
Study type: Interventional

This is a randomized, double-blind, placebo-controlled trial, designed to evaluate the efficacy and safety of SAGE-547 administered as a continuous intravenous infusion to subjects in Super-Refractory Status Epilepticus (SRSE).

NCT ID: NCT02473965 Completed - Myasthenia Gravis Clinical Trials

Efficacy and Safety of IGIV-C in Corticosteroid Dependent Patients With Generalized Myasthenia Gravis

Start date: June 2015
Phase: Phase 2
Study type: Interventional

This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of Immune Globulin (Human), 10% Caprylate/Chromatography Purified (IGIV-C) as a corticosteroid (CS)-sparing agent in subjects with CS-dependent Myasthenia Gravis (MG).

NCT ID: NCT02473952 Completed - Clinical trials for Myasthenia Gravis, Generalized

A Study to Evaluate the Efficacy and Safety of IGIV-C in Symptomatic Subjects With Generalized Myasthenia Gravis

Start date: August 2015
Phase: Phase 2
Study type: Interventional

The primary objective is to evaluate whether IGIV-C improves MG symptoms as compared to placebo in subjects with MG.

NCT ID: NCT02472886 Completed - Clinical trials for Hepatitis C Virus Infection

Safety and Efficacy of Ledipasvir/Sofosbuvir in Adults With Chronic HCV Infection

Start date: June 17, 2015
Phase: Phase 3
Study type: Interventional

The primary objectives of this study are to evaluate the antiviral efficacy, safety, and tolerability of ledipasvir/sofosbuvir (LDV/SOF) fixed dose combination (FDC) with or without ribavirin (RBV) in adults with chronic hepatitis C virus (HCV) infection.

NCT ID: NCT02471144 Completed - Clinical trials for Chronic Severe Plaque-type Psoriasis

Pediatric Study in Children and Adolescents With Severe Plaque Psoriasis

Start date: September 29, 2015
Phase: Phase 3
Study type: Interventional

This was a multicenter, randomized, double-blind, placebo- and active-controlled (etanercept in single blinded arm) study in pediatric subjects aged 6 years to less than 18 years with severe chronic plaque psoriasis. Approximately 160 subjects aged 6 years to <18 years were enrolled, of which at least 30 were 6 years to <12 years old. Subjects were enrolled at approximately 70 study sites worldwide.

NCT ID: NCT02470312 Terminated - Heart Failure Clinical Trials

MediGuide Registry

Start date: August 18, 2015
Phase:
Study type: Observational [Patient Registry]

The goal of this registry/observational study is to collect data on the clinical utility of MediGuideā„¢ system in cardiac resynchronization therapy (CRT) implantation and electrophysiology (EP) procedures.

NCT ID: NCT02455999 Completed - Dry Eye Syndrome Clinical Trials

Dose-finding Study to Assess the Safety and Effect of SYL1001 in Patients With Ocular Pain

Start date: June 2015
Phase: Phase 2
Study type: Interventional

The aim of this pilot study is to compare the analgesic effect of two strengths of SYL1001 eye drops versus placebo in patients with ocular pain associated with Dry Eye Syndrome. General and local tolerability are also evaluated.

NCT ID: NCT02442765 Completed - Clinical trials for Agitation in Patients With Dementia of the Alzheimer's Type

Efficacy, Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type

Start date: July 23, 2015
Phase: Phase 3
Study type: Interventional

Participants with agitation secondary to dementia of the Alzheimer's type. The diagnosis of probable Alzheimer's disease (AD) was to be based on the "2011 Diagnostic Guidelines for Alzheimer's Disease" issued by the National Institute on Aging (NIA)-Alzheimer's Association (AA) workgroups.