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NCT ID: NCT02337179 Completed - HIV Clinical Trials

Male Circumcision Services for HIV Prevention in the Dominican Republic

Start date: February 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the feasibility of introducing voluntary medical male circumcision as a form of HIV prevention in high HIV prevalence areas in the Dominican Republic.

NCT ID: NCT02309554 Completed - Contraception Clinical Trials

Postcoital Testing Study of the SILCS Diaphragm Used With 3% N-9 Gel, ContraGel, or No Gel

Start date: December 2014
Phase: Phase 1
Study type: Interventional

This post coital test study is a Phase I multi-center, randomized, crossover, non-significant risk device study to be carried out at two clinical sites/centers. The products to be tested are the SILCS diaphragm with 3% Nonoxynol-9 Gel (N-9) (spermicide), the SILCS diaphragm with ContraGel, and the SILCS diaphragm alone. Participants will be randomized to the order of product use, with a goal of 10 participants completing the study.

NCT ID: NCT02307201 Completed - Clinical trials for Post Partum Severe Preeclampsia

Magnesium Sulfate During the Postpartum in Women With Severe Preeclampsia

MAG-PIP
Start date: December 2014
Phase: Phase 2/Phase 3
Study type: Interventional

There is no evidence that patients receiving magnesium sulfate before birth are required to maintain the drug for 24 hours. Therefore the investigators will have a randomized clinical study in patients with severe preeclampsia who have been treated with impregnation of magnesium sulphate and at least eight hours have received the drug before birth. If the patient agrees and signs the consent is randomized to: 1-receive sulfate for 24 hours postpartum as usual or, 2- not receiving the postpartum magnesium sulfate or other anticonvulsant drugs. This study can be conducted in 12 maternity latin america.

NCT ID: NCT02302066 Completed - Dengue Fever Clinical Trials

Safety and Immunogenicity of Different Schedules of Takeda's Tetravalent Dengue Vaccine Candidate (TDV) in Healthy Participants

Start date: December 5, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the humoral immune responses to three different dose schedules of Takeda's Tetravalent Dengue Vaccine Candidate (TDV) administered subcutaneously in healthy participants between 2 and <18 years of age living in dengue endemic countries.

NCT ID: NCT02243046 Completed - Clinical trials for Dental Plaque and Gingivitis

The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis

Start date: December 2014
Phase: Phase 2
Study type: Interventional

This is a six (6) month, double-blind, parallel, controlled clinical trial utilizing one hundred and sixty (160) adults to evaluate the reduction of dental plaque and gingivitis.

NCT ID: NCT02235662 Completed - HIV Clinical Trials

Phase I One-month Safety, PK, PD, and Acceptability Study of IVR Releasing TFV and LNG or TFV Alone

Start date: October 2014
Phase: Phase 1
Study type: Interventional

The purpose of the study is to evaluate the safety of the TFV/LNG intravaginal ring (IVR), TFV-only IVR, and placebo IVR, evaluate pharmacokinetics (PK) of TFV and LNG, evaluate pharmacodynamic (PD) surrogates of contraceptive efficacy of LNG, and to evaluate acceptability of the IVRs.

NCT ID: NCT02227290 Completed - Tinea Corporis Clinical Trials

Pediatric Subjects With Tinea Corporis

Start date: August 2014
Phase: Phase 4
Study type: Interventional

The study is being done to see how well the study cream works when applied once a day to affected area of child (where they have ringworm). The results will be compared to those seen with a placebo cream which has no active ingredient. Safety of the cream will also be measured.

NCT ID: NCT02210689 Completed - BACTERIAL VAGINOSIS Clinical Trials

A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment of Bacterial Vaginosis in Non-pregnant Women

Start date: January 2014
Phase: Phase 3
Study type: Interventional

A multi-center, double-blind, randomized, placebo controlled, parallel-group study, comparing Clindamycin phosphate vaginal cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and both active treatments to a placebo control in the treatment of bacterial vaginosis in non-pregnant women.

NCT ID: NCT02167763 Completed - Clinical trials for Prevention of Pregnancy

Comparative Study of the VeraCept Low-Dose Intrauterine Copper Contraceptive vs. the TCu380 Copper IUD

Start date: November 2013
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and effectiveness of the VeraCept Low Dose Intrauterine Copper Contraceptive compared to the standard T shaped copper IUD, the TCu380.

NCT ID: NCT02161562 Completed - Clinical trials for Chronic Spontaneous Urticaria

OPTIMA: Efficacy of Optimized Re-treatment and Step-up Therapy With Omalizumab in Chronic Spontaneous Urticaria (CSU) Patients

OPTIMA
Start date: August 1, 2014
Phase: Phase 3
Study type: Interventional

This trial assessed the efficacy of optimized re-treatment therapy with omalizumab (150mg or 300mg) after relapse, in participants with Chronic Spontaneous Urticaria who were clinically well-controlled following their first course of treatment with omalizumab (150mg or 300mg). The study also assessed the benefit of uptitrating to 300mg dose in participants who were not well-controlled following their initial course of treatment with omalizumab 150mg, as well as the benefit of treatment extension of those patients who were not well-controlled following their initial course of treatment with omalizumab 300mg.